Friedel-Crafts acylation formed by attack at the meta positions of Nitrobenzene. (-NH2 and-OH) act as powerful activators toward electrophilic aromatic substitution.

Q: methylbenzene with propanoyl chloride and AIICI3 to make `CH2-CH3 H3C

A: The mechanism for the electrophilic substitution of the acyl group of propanoyl chloride and methyl…

Q: Which or which of the statements given below is correct. I) Maleic anhydride is a carboxylic acid…

A: (I) Maleic anhydride is a carboxylic acid derivative which on reaction with water gives the…

Q: Account for the following:(i) Aniline does not give Friedel-Crafts reaction.(ii) Ethylamine is…

A: Friedel Craft reaction is an E+ aromatic substitution reaction in which alkyl or acyl substituents…

Q: From 1 being the slowest and 4 being the fastest rank the aromatic hydrocarbons in terms of…

A: The compounds given are,

Q: Which of the following is most susceptible towards nucleophilic aromatic substitution?

A: The aromatic nucleophilic substitution reaction follows addition elimination mechanism.

Q: tarting with Benzene, outline how m-chlorobenzoic acid would be best prepared. The sequence of eps…

A: Synthesis of m-chlorbenzoic acid is as follows -

Q: Provide the best retrosynthesis nantanol an ner

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Q: :Explain the following Diazotization reaction carried out during the preparation of p-iodotoluene…

A: Diazotization reactions:

Q: enzoate. The nitro substituent was introduced in the meta position of the methy Why does it…

A: It is due to the -R effect of the COCH3 gruop, a positive charge will be generated at the ortho- and…

Q: What is the likely mechanism of nucleophilic substitution for attached alkyl halide?

A: As there is no attached alkyl halide in the question. So discuss general mechanism of nucleophilic…

Q: Rank the following according to increasing reactivity with 1 as the least reactive, and 4 as the…

A: The reactivity order for nucleophilic acyl substitution is as follows:

Q: Outline a synthesis of each Wittig reagent from Ph3P and an alkyl halide.

A: Given:

Q: e) "Pyridine does not readily undergo electrophilic aromatic substitution, but it can undergo…

A: Interpretation -  Briefly explain the statement and give the example of typical nucleophilic…

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A: Recall electronic effects and intermediates with important reactions.

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Q: Is a intramolecular Friedel Crafts acylation reaction. As you from the product, the acylation…

A: Applying concept of organic synthesis and reagent.

Q: Arrange these compounds in order of reactivity towards electrophilic aromatic

A: The reactivity of aromatic compounds in electrophilic substitution reaction is depends on groups…

Q: Aromatics can be converted into nitroaromatics upon treatment with a mixture of nitric and sulfuric…

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Q: A compound X on reductive ozonolysis gives ethanal, methanal and carbon-dioxide. X is

A: Ozonolysis is the reaction of alkenes with ozone to form aldehydes and ketones. The given products…

Q: How common electron-donating and electron-withdrawinggroups affect both the rate of reaction of a…

A: The substitution of an atom or group of atom through an electrophile is termed as electrophilic…

Q: 1. Explain the the following,giving examples and illustrations to support your answer Electrophilic…

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Q: Please explain the following clearly. 1.Benzene undergoes electrophilic aromatic Substitution rxns.…

A: As per our guidelines, we can only solve one question at a time please post other questions as next…

Q: Carboxylic acids are lowest in reactivity towards nucleophilic substitution. Why? (Consider the…

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Q: How to determine the relative basicity of nitrogen heterocycles ?

A: Heterocyclic compounds are aromatic hydrocarbons with one or two hetero atoms like O or N. Some well…

Q: Which ester, C or D, is more reactive in nucleophilic acyl substitution?Explain your reasoning.

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Q: Why are the cyanates and sulfonates not as toxic as the other compounds of cyanide?

A: Cyanide is the CN-particle, and as a harm it is generally controlled as one of the three mixtures…

Q: Express the reaction of α,β-Unsaturated Carbonyl Compounds with Organometallic Reagents ?

A: Grignard reagent reacts directly with the carbonyl C, that is, it shows 1,2 addition. Gilman reagent…

Q: Using resonance structures, explain why a nitroso group (– NO) is an ortho, para director that…

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Q: Rank the species below in order of increasing nucleophilicity in protic solvent.

A: Nucleophile are species which have excess of electron density either have filled orbital or lone…

Q: Give Four main precautions need to be considered when carrying out the following. b) Synthesis of…

A: Benzopinacole (white color precipitate) generation is done via photoreduction method. It is highly…

Q: Give the correct order of the given compounds in order of decreasing reactivity towards…

A: Aromatic electrophilic substitution reaction: Aromatic electrophilic substitution reactions are the…

Q: Which of the following statements is FALSE? OA Bromobenzene is less reactive than benzene in an…

A: All the electron donating substituents on the ring activates the ring towards electrophilic aromatic…

Q: Arrange the compounds in  set in order of decreasing reactivity (fastest to slowest) toward…

A: Given compounds,

Q: Outline a synthesis of each Wittig reagent from Ph3P and an alkyl halide.

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Q: C!

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Q: Which one  would be most reactive toward electrophilic aromatic substitution?

A: Aromatic electrophilic substitution reaction: Aromatic electrophilic substitution reactions are the…

Q: Give the structures of A and B in the following reactions. Pay special attention to stereochemistry.…

A: m-CPBA (meta chloro per benzoic acid)--->> It is used for epoxidation of alkene and also used…

Q: Benzoyl chloride undergoes nucleophilic substitution at a faster rate than methyl propanoate because

A: Nucleophilic attacks on both benzoyl chloride and methyl propanoate are examples of nucleophilic…

Q: s the following statement true or false? "Friedel-Crafts alkylation of aniline is not possible, due…

A: Freidel crafts reactions  are of two types alkylation reaction and acylation reaction, these  two…

Q: Order of reactivity towards nucleophilic substitution reaction of the compounds

A: Order of the reactivity towards nucleophillic substitution reaction of the compound

Q: Identify the ring which is more reactive towards electrophilic aromatic substitution.

A: Electrophiles are electron deficient system that are attracted to electron system. Electrophilic…

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Q: (−)-Hyoscyamine, an optically active drug used to treat gastrointestinal disorders, is isolated from…

A: a). (-)-Hyoscyamine contains two hydrogens which are acidic, which are benzylic and alcoholic…

Q: Explain why the halogens, when attached to a benzene ring, weakly deactivate the ring toward…

A: Halogens bonded to benzene ring has three lone pairs. These three electron pairs can cause resonance…