Given: A weak acid, HA (whose Ka is 1.00 x 10-6 and KD is 100) that distributes between benzene and water. a. Show how that the distribution ratio, D, of the acid is a function of the partition coefficient, KD, [H*] and Ka. Recall that D= [total concentration of all forms of HA]org [tota conentration of all forms of HA]aq b. calculate the its distribution ratio if the pH of the aqueous phase is neutral. The acid is a monomer in the benzene phase.

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Given: A weak acid, HA (whose Ka is 1.00 x 10-6 and Kp is 100) that
distributes between benzene and water.
a. Show how that the distribution ratio, D, of the acid is a function of
the partition coefficient, KD, [H*] and Ka.
Recall that D= [total concentration of all forms of HA]org
[tota conentration of all forms of HA]aq
b. calculate the its distribution ratio if the pH of the aqueous phase is
neutral. The acid is a monomer in the benzene phase.
Transcribed Image Text:Given: A weak acid, HA (whose Ka is 1.00 x 10-6 and Kp is 100) that distributes between benzene and water. a. Show how that the distribution ratio, D, of the acid is a function of the partition coefficient, KD, [H*] and Ka. Recall that D= [total concentration of all forms of HA]org [tota conentration of all forms of HA]aq b. calculate the its distribution ratio if the pH of the aqueous phase is neutral. The acid is a monomer in the benzene phase.
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