Given your understanding of Wolff’s Law, what mechanical consideration would be important when designing a bioreactor for osteocyte growth ex vivo?
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- One of the major promoters of bone remodelling and increased bone thickness is mechanical stress on the bone. Explain this mechanism and give an example.Describe the role of collagen and seed crystals in bonemineralizationWhat role do biophysical and biochemical context play in development structure for bone in load bearing? (in bullet form)
- Why might a person suffering from osteoporosis benefit from increased calcium ingestion?Compare how the different osteocytes in both compact and spongy cells are affected in osteoporosis. Don’t forget to include how the organic material like calcium and phosphorus are affected in osteoporosis.Osteocytes residing in lacunae of osteons of healthy compact bone are located quite a distance from the blood vessels in the central canals, yet they are well nourished. How can this be explained?
- Please answer this following question in your own words. Question 1: List and describe 3 major functions of the skeletal system? Question 2: Compare and contrast compact and spongy bone? Question 3: Describe the effect exercise has on bone tissue? Question 4: Define the 4 types of bone cells, Osteocytes, osteoblasts, osteoclasts, and osteoprogenitor im your own words?Because of the constant exchange of blood calcium and bone calcium, the concentration of calcium ions in the blood and tissue is very steady. Describe the process of calcium mobilization in bone tissue.Briefly describe the structure and function of bone tissue. What are the basic design requirements for bone tissue engineering scaffolds?
- Disturbance of the balance in the activities of osteoblasts and osteoclasts in favor of osteoclasts can give rise to the condition known as osteoporosis, the brittle-bone syndrome of the elderly. Explain why or why not.Give one condition of imbalance between bone modeling and remodeling, Explain briefly the mechanism.What is relationship between estrogens and osteoporosis development?
