Heterozygotes for erythropoietic protoporphyria show only 20 to 30% residual ferrochelatase activity rather than the 50% that is normally expected for an autosomal dominant inherited disease. Provide a plausible explanation for this observation.

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter16: Adult And Pediatric Dosages Based On Body Surface Area
Section: Chapter Questions
Problem 20SST
icon
Related questions
Question

Heterozygotes for erythropoietic protoporphyria show only 20 to 30% residual ferrochelatase activity rather than the 50% that is normally expected for an autosomal dominant inherited disease. Provide a plausible explanation for this observation.

Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Prokaryotic evolution
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Curren'S Math For Meds: Dosages & Sol
Curren'S Math For Meds: Dosages & Sol
Nursing
ISBN:
9781305143531
Author:
CURREN
Publisher:
Cengage
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning