Benign prostatic hyperplasia is a noncancerous enlargement of the prostate gland that adversely affects the quality of life (QoL) of millions of men. A study of minimally invasive procedures for the treatment for this condition looked at pretreatment QoL (qol_base) and quality of life after 3 month on treatment (qol_3mo) The baseline data for 10 patients and their 3 month follow-up data is presented below: MAXFLO_B = maximum urine flow at baseline (urine flow measurement scale misplaced) MAXFLO3M = maximum urine flow after 3 months of treatment maxflo_b maxflo3m 7 8 18
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- That animal species produce more offspring when their supply of food goes up isn’t surprising. That some animals appear able to anticipate unusual food abundance is more surprising. Red squirrels eat seeds from pine cones, a food source that occasionally has very large crops (called seed masting). What is striking is that the offspring are conceived in the spring, before the cones mature in the fall to feed the new young squirrels through the winter. Here are data on an index of the abundance of pine cones and average number of offspring per female over 16 years: Pine Index x 0 2.02 0.25 3.22 4.68 0.31 3.37 3.09 2.44 4.81 1.88 0.31 1.61 1.88 0.91 1.04 Offspring y 1.49 1.1 1.29 2.71 4.07 1.29 3.36 2.41 1.97 3.41 1.49 2.02 3.34 2.41 2.15 2.12 (a) Describe the relation between the variable x (Pine index) and the variable y (offspring) using the correlation factor r. Explain what r tells us about the relation. (b) Find the expected y value for a year when the Pine…There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that they can be harnessed to use the body's immune system to treat cancer. One study investigated the use of a T cell-engaging antibody, blinatumomab, to recruit T cells to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study) and after 20 days on blinatumomab for six subjects in the study.† The difference (after 20 days minus baseline) is the response variable. Baseline: 0.04 0.02 0.00 0.02 0.38 0.33 After 20 days: 0.28 0.47 1.30 0.25 1.22 0.44 Difference: 0.24 0.45 1.30 0.23 0.84 0.11 Do the data give convicing evidence that the mean count of T cells is higher after 20 days on blinatumomab?A study was undertaken in a hospital to compare the performance of a new surveillance method to the standard method in the ability to detect patients who develop an infection after a caesarean section. Individual record data from this study is provided in the file called surveillence.dta. The dataset contains the following variables: ID: Patient identification number new: Assessment of cases by the new surveillance method (1=Positive, 2=Negative) standard: Assessment of cases by the standard method (1=Positive, 2=Negative) ID new standard 1 negative negative 2 negative negative 3 negative negative 4 negative negative 5 negative negative 6 negative negative 7 negative negative 8 negative negative 9 negative negative 10 negative negative 11 negative negative 12 negative negative 13 negative negative 14 negative negative 15 negative negative 16 negative…
- Males under the age of 25 must pay far higher auto insurance premiums than females in this age group. How does this fact relate to statistical discrimination? Statistical discrimination implies that discrimination can persist indefifinitely, while the taste-for-discrimination model suggests that competition might reduce discrimination in the long run. Explain the difference.Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 80th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 9.18 (Note: These are the same data as in Table 8.27, p. 329). 9.71 Compare your results in Problems 9.69 and 9.70. 9.72 Compare your results to those obtained using t test methods in Problem…Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 80th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 9.18 (Note: These are the same data as in Table 8.27, p. 329). 9.68 What is the critical region at the 5% level? (i.e., for what values of the test statistic will we reject H0 at the 5% level?)…
- Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 80th percentile for their age, gender, and height)and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after4 years of follow-up. The data are given in images. a) Suppose the investigators are reluctant to assume that the change in LVM over four years is normally distributed. What test can be used to assess if there is a change in mean LVM over four…Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 80th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 9.18 (Note: These are the same data as in Table 8.27, p. 329). 9.65 Suppose the investigators are reluctant to assume that the change in LVM over four years is normally distributed. What test…Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 80th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period.To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 9.18. A)Suppose the investigators are reluctant to assume that the change in LVM over four years is normally distributed. What test can be used to assess if there is a change in mean LVM over…
- Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 80th percentile for their age, gender, and height)and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after4 years of follow-up. The data are given in images. Problem a)What is the two-sided p-value for this test?Problem b)Now perform the test using the exact method andobtain a 2-sided p-value.Problem c) Compare your results in Problems a and b.Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 90th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 1 . Table 1 Pilot data on left ventricular mass (LVM) in children from the Bogalusa Heart Study ID Baseline LVM (g) 4- year LVM (g) Change (g)* 1 139 163 24 2 134 126 -8 3 86 142 56…Muscle tension in the head region has been associated with tension headaches. Therefore, a physician reasoned that if the muscle tension could be reduced, perhaps the headaches would decrease or go away altogether. They design an experiment in which nine participants with tension headaches participate. The participants keep the logs of number of headaches experience during a two week baseline period. Then they are trained to lower their muscle tension in the head region, using a biofeedback device. For this experiment, the biofeedback device is connected to the frontalis muscle, a muscle in the forehead region. The device tells the participant the amount of tension in the muscle to which it is attached ( in this case, frontalis) and helps them achieve low tension levels. After six weeks of training, during which the participants have become successful at maintaining low frontalis muscle tension, They again keep a two week log of the number of headaches experience. The following are…