How would you identify patients whose tumor cells are particularly likely to have a somatic mutation in the PTEN gene that is outside of the codingregion but nonetheless contributes to cancer by affecting the gene’s regulation?

How would you identify patients whose tumor cells are particularly likely to have a somatic mutation in the PTEN gene that is outside of the codingregion but nonetheless contributes to cancer by affecting the gene’s regulation?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 21QP: Transcriptional regulators are proteins that bind to promoters (the 5-flanking regions of genes) to...

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How would you identify patients whose tumor cells are particularly likely to have a somatic mutation in the PTEN gene that is outside of the coding
region but nonetheless contributes to cancer by affecting the gene’s regulation?

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