Imagine you do a version of the Beadle-Tatum experiment in which you attempt to test the one-gene, one-enzyme hypothesis, but using the pathway of synthesis of amino acid Q from X (below). The reactions, in order, are catalyzed by enzymes E1-E5. X is always present in cells, and cells need Q to grow. E1 E2 ЕЗ E4 E5 X Y Z - P D Q You identify a mutant strain that doesn't grow in normal medium, but does grow in medium supplemented with Q, indicating that it has a defect in one or more enzymes in this pathway. The only other piece of data you have is that this strain is also able to grow if you supplement the medium with Z. Is this data evidence for the one gene-one enzyn hypothesis? O no, because this doesn't rule out the possibility that both Enzymes 1 and 2 are disrupted O yes, because enzymes 3, 4, and 5 are functional in the mutant O yes, because only one enzyme is disrupted by the mutation thic tollo HOu thnt como amer in the pathway are still functional

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 36
Imagine you do a version of the Beadle-Tatum experiment in which you attempt to test the one-gene, one-enzyme
hypothesis, but using the pathway of synthesis of amino acid Q from x (below). The reactions, in order, are catalyzed
by enzymes E1-E5. X is always present in cells, and cells need Q to grow.
Е1
E2
ЕЗ
E4
E5
X Y Z - P D Q
|
You identify a mutant strain that doesn't grow in normal medium, but does grow in medium supplemented with Q,
indicating that it has a defect in one or more enzymes in this pathway. The only other piece of data you have is that this
strain is also able to grow if you supplement the medium with Z. Is this data evidence for the one gene-one enzyme
hypothesis?
O no, because this doesn't rule out the possibility that both Enzymes 1 and 2 are disrupted
O yes, because enzymes 3, 4, and 5 are functional in the mutant
O yes, because only one enzyme is disrupted by the mutation
O no, because this tells you that some of the enzymes in the pathway are still functional
Transcribed Image Text:QUESTION 36 Imagine you do a version of the Beadle-Tatum experiment in which you attempt to test the one-gene, one-enzyme hypothesis, but using the pathway of synthesis of amino acid Q from x (below). The reactions, in order, are catalyzed by enzymes E1-E5. X is always present in cells, and cells need Q to grow. Е1 E2 ЕЗ E4 E5 X Y Z - P D Q | You identify a mutant strain that doesn't grow in normal medium, but does grow in medium supplemented with Q, indicating that it has a defect in one or more enzymes in this pathway. The only other piece of data you have is that this strain is also able to grow if you supplement the medium with Z. Is this data evidence for the one gene-one enzyme hypothesis? O no, because this doesn't rule out the possibility that both Enzymes 1 and 2 are disrupted O yes, because enzymes 3, 4, and 5 are functional in the mutant O yes, because only one enzyme is disrupted by the mutation O no, because this tells you that some of the enzymes in the pathway are still functional
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