The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation. Mutation DNA Sequence ..ATGGGCGAGGTA TTATA G.. 3' None 5' A ..A TGGGCGAGATATTATA G.. 3' 5' B ..A TG G GCGAGGTA CTATA G.. 3' 5' 5' ..A TGG C CGAGGTAT TATA G.. 3' The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein A Transition B Transition C Transversion Nonsense Synonymous Nonsynonymous

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
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Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...
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The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence
with no mutations. Subsequent rows represent a single mutation.
Mutation
DNA Sequence
..ATGGGCGAGGTATTATA G.. 3'
None 5'
A
..A TGGGCGAGATATTATA G.. 3'
5'
B
..ATGGG CGAGGT ACTAT A G.. 3
5'
5'..A TGGC C GAGGTATTATAG.. 3'
The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino
acids with no spaces.
N-
-C
Determine the molecular basis for each mutation and what effect there would be on the protein.
Mutation Molecular Basis
Effect on Protein
A
Transition
Transition
Transversion
Nonsense
Synonymous
Nonsynonymous
Readthrough
Transcribed Image Text:The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation. Mutation DNA Sequence ..ATGGGCGAGGTATTATA G.. 3' None 5' A ..A TGGGCGAGATATTATA G.. 3' 5' B ..ATGGG CGAGGT ACTAT A G.. 3 5' 5'..A TGGC C GAGGTATTATAG.. 3' The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- -C Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein A Transition Transition Transversion Nonsense Synonymous Nonsynonymous Readthrough
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