In a parental cross of a ADHL disease trait, where the father is affected and the mother is unaffected, 50% of the offspring will have the disease phenotype and 50% will have the WT phenotype. In an F₁ cross between an unaffected male and an unaffected female, the respective expected proportions of the disease phenotype and WT phenotype in the F2 generation are: 1.0 and 0.0. 0 and 1.0. X 0.75 and 0.25. 0.50 and 0.50. 0.667 and 0.333.

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Chapter5: The Inheritance Of Complex Traits
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In a parental cross of a ADHL disease trait, where the father is affected and the mother is unaffected, 50% of the offspring will have the disease
phenotype and 50% will have the WT phenotype. In an F₁ cross between an unaffected male and an unaffected female, the respective expected
proportions of the disease phenotype and WT phenotype in the F2 generation are:
1.0 and 0.0.
0 and 1.0.
0.75 and 0.25.
0.50 and 0.50.
0.667 and 0.333.
Transcribed Image Text:In a parental cross of a ADHL disease trait, where the father is affected and the mother is unaffected, 50% of the offspring will have the disease phenotype and 50% will have the WT phenotype. In an F₁ cross between an unaffected male and an unaffected female, the respective expected proportions of the disease phenotype and WT phenotype in the F2 generation are: 1.0 and 0.0. 0 and 1.0. 0.75 and 0.25. 0.50 and 0.50. 0.667 and 0.333.
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In the given case, let the dominant allele associated with ADHL disease be “A” and the allele associated with normal condition be “a”. The genotypes of parents here would be “Aa” (father) and “aa” (mother), as 50% of offspring are normal.

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