In a tissue engineering experiment, stem cells are grown in a circular dish (diameter = 3 cm) with a thin layer of cell culture media covering the cells. It is expected that these cells will differentiate when exposed a new differentiation factor (small molecule) at a surface concentration of 50 ng/cm? During the experiment, 1 ug of the factor is placed at the center of the dish. Assume the diffusivity of the factor in cell culture media is 1 x 10^-5 cm^2/s. A. How long does it take before the cells 1 cm from the center of the dish begin to differentiate? B. Do you expect the cells at the edge of the dish differentiate? Justify your answer with calculations.

In a tissue engineering experiment, stem cells are grown in a circular dish (diameter = 3 cm) with a thin layer of cell culture media covering the cells. It is expected that these cells will differentiate when exposed a new differentiation factor (small molecule) at a surface concentration of 50 ng/cm? During the experiment, 1 ug of the factor is placed at the center of the dish. Assume the diffusivity of the factor in cell culture media is 1 x 10^-5 cm^2/s. A. How long does it take before the cells 1 cm from the center of the dish begin to differentiate? B. Do you expect the cells at the edge of the dish differentiate? Justify your answer with calculations.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 1QP: The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show...

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