In the disease familial hypercholesterolemia (inherited tendency for high blood LDL cholesterol levels), the protein that helps clear cholesterol from the blood (called the LDL receptor) has a single amino acid that is different from the normal protein. This amino acid change greatly reduces the ability to clear cholesterol from the blood, resulting in high cholesterol levels and the risk of heart attack. Which of the following are different (compared to normal) in the person suffering from familial hypercholesterolemia? __The sequence of the mRNA that encodes for the LDL receptor. __The DNA sequence of the gene for the LDL receptor. __The presence of the gene for the LDL receptor. __The amino acid sequence of the LDL receptor.

In the disease familial hypercholesterolemia (inherited tendency for high blood LDL cholesterol levels), the protein that helps clear cholesterol from the blood (called the LDL receptor) has a single amino acid that is different from the normal protein. This amino acid change greatly reduces the ability to clear cholesterol from the blood, resulting in high cholesterol levels and the risk of heart attack. Which of the following are different (compared to normal) in the person suffering from familial hypercholesterolemia? The sequence of the mRNA that encodes for the LDL receptor. The DNA sequence of the gene for the LDL receptor. The presence of the gene for the LDL receptor. The amino acid sequence of the LDL receptor.

Nutrition Now

8th Edition

ISBN:9781337415408

Author:Brown

Publisher:Brown

Chapter16: Vegetarian Dietary Patterns

Section: Chapter Questions

Problem 7RQ

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Four of the most abundant amino acids in proteins are leucine, alanine, glycine, and valine. What do these amino acids have in common? Would you expect these amino acids to be found on the interior or on the exterior of theprotein?
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Glucagon is a peptide hormone consisting of 29 residues that are released into the blood. It works with insulin to regulate blood sugar levels, when blood sugar is low, glucagon is a signal to release glucose into the blood from glucose stored in long chains called glycogen. When blood sugar is high, insulin signals to cells to take in glucose and convert into glycogen. Glucagon is an inherently unstructured peptide that does not adopt any definitive fold until it interacts with the glucagon receptor. Based upon what you know about the structure of CBP’s NCBD region. Which of the following are true? Before binding the structure is at the middle of the protein-folding funnel. Before binding the structure is at the bottom of the protein-folding funnel. It exists as a molten globule B and C A and C
Glucagon is a peptide hormone consisting of 29 residues that are released into the blood. It works with insulin to regulate blood sugar levels, when blood sugar is low, glucagon is a signal to release glucose into the blood from glucose stored in long chains called glycogen. When blood sugar is high, insulin signals to cells to take in glucose and convert into glycogen. Glucagon is an inherently unstructured peptide that does not adopt any definitive fold until it interacts with the glucagon receptor. : I have been forced to use molecular exclusion as a first purification step. Which of the following would be true? I will use a acetonitrile as a mobile phase I will use a water based salt buffer as my mobile phase. To obtain a native fold, I will need to use dialysis to remove excess salt and to change the PH. A and C B and C
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