Most inherited forms of cancer show a dominant pattern of inheritance in a pedigree. An example is a mutation in the BRCA-1 gene. However, the formation of cancer is recessive at the cellular level. Also, although BRCA-1 is inherited in a dominant fashion, it sometimes skips generations. Explain how these facts are possible.

Biology: The Unity and Diversity of Life (MindTap Course List)
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Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
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10. Most inherited forms of cancer show a dominant pattern of inheritance in a pedigree. An example is a
mutation in the BRCA-1 gene. However, the formation of cancer is recessive at the cellular level. Also,
although BRCA-1 is inherited in a dominant fashion, it sometimes skips generations. Explain how these
facts are possible.
Transcribed Image Text:10. Most inherited forms of cancer show a dominant pattern of inheritance in a pedigree. An example is a mutation in the BRCA-1 gene. However, the formation of cancer is recessive at the cellular level. Also, although BRCA-1 is inherited in a dominant fashion, it sometimes skips generations. Explain how these facts are possible.
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