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Science

Biology

Most Mutations that Affect GeneExpression Reduce Gene Function WHy?

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter28: Dna Metabolism: Replication, Recombination, And Repair

Section: Chapter Questions

Problem 14P

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Concept explainers

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.

Topic Video

Question

Most Mutations that Affect Gene
Expression Reduce Gene Function WHy?

Expert Solution

Step 1

Gene contains the sequence of the amino acids which is transcribed into mRNA and translated into protein. Protein is responsible for expression of the gene.

Step 2

Now, mutation occurs in the gene. As a result, the sequence of the protein which is encoded by the gene may alter.

So, after translation, a non-functional protein is produced.

As the protein is responsible for expression of the gene but the non-functional protein can't function efficiently.

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