NEt NEt, several steps OEL atorvestatin

Q: Reaction of X and phenylacetic acid forms an intermediate Y, which undergoes an intramolecular…

A:

Q: Identify X, an intermediate that was converted to eletriptan (trade name Relpax), a drug used to…

A: EXPLANATION: This is very important and modern reaction involved in organic chemistry is the Heck…

Q: Draw the product that is expected when the β-pyranose form of compound A is treated with excess…

A: The structure of D-glucose is given below:

Q: Biyouyanagin A is an anti-HIV agent isolated from the leaves of a plant of the genus Hypericum that…

A: SOLUTION: Step 1: Biyouyanagin A is an anti-HIV agent isolated from the leaves of Hypericum chinense…

Q: Draw the electron pushing reaction mechanism for the hydrolysis of the artificial sweetener…

A: Aspartame on hydrolysis gives aspartic acid, phenyl alanine and methanol under acidic, basic and…

Q: Treatment of cholesterol with MCPBA results in formation of a single epoxide A, with the…

A: Stereoselectivity is the property of a Compound or reaction in which a single reactant forms an…

Q: (a) Explain how NaBH4 in CH3OH can reduce hemiacetal A to butane-1,4-diol (HOCH2CH2CH2CH2OH). (b)…

A: The reaction of hemiacetal A will be given by the sodium borohydride in presence of methanol as-

Q: Treatment of cholesterol with mCPBA results in formation of a single epoxide A, with the…

A:

Q: Nabumetone is a pain reliever and anti-inammatory agent sold under the brand name of Relafen.a.…

A: a.

Q: (a) Explain how NaBH4 in CH3OH can reduce hemiacetal A to butane-1,4-diol (HOCH2CH2CH2CH2OH). (b)…

A: (a) The given compound A is a hemiacetal. Sodium borohydride (NaBH4) is a strong reducing agent. It…

Q: Devise a synthesis of optically active (S)-fluoxetine (trade name Prozac) from the given starting…

A: Oxidizing agents in organic chemistry- For oxidation of organic compound various reagents can be…

Q: Draw the organic products formed in the following reaction.

A: The first step is the reaction of given mixture of enantiomers of amino acid with acetic anhydride…

Q: Synthesize the compund (Nimodipine) via Hantzsch dihydropyridine synthesis

A: Nimodipine is a medicine used to treat symptoms resulting from a ruptured blood vessel in the brain.…

Q: What two aldohexoses yield D-arabinose upon Wohl degradation?

A: Aldohexose produce aldopentose through Wohl degradation (chain shortening).

Q: Identify C and D in the following reaction scheme, two steps in the synthesis of the…

A: The formation of compound C is shown below.

Q: Reaction of X and phenylacetic acid forms an intermediate Y, which undergoes an intramolecular…

A: In the given reaction, the base abstracts the acidic proton from carboxylic acid. The phenyl acetate…

Q: Devise a synthesis of optically active (S)-fluoxetine (trade name Prozac) from the given starting…

A: Given,

Q: Slow addition of organolithium reagent A to B afforded C, an intermediate in the synthesis of the…

A: Stepwise mechanism for this process can be drawn as

Q: One step in the synthesis of periplanone B, the chapter-opening molecule, involved anionic oxy-Cope…

A: Anionic oxy-Cope rearrangement is a thermal [3,3]-sigmatropic rearrangement.  This rearrangement…

Q: Eudesmol is a sesquiterpene found in eucalyptus. Propose a mechanism for its biosynthesis.

A:

Q: nthesis, show two different synthesis strategies. In the first synthesis strategy, include e…

A: The questions based on organic reactions. We have to convert the reactant into product by a series…

Q: н. CH3 CH3ONA H3C CH3 CH3OH

A: Epoxide openning in basic medium is the SN2 reaction .

Q: Treatment with sodium borohydride converts aldose A to an optically inactive alditol. Wohl…

A: A and B has to be identified.

Q: 19. a.) Autoxidation is a process that ages chemical solvents and fatty acids by producing toxic and…

A: Autoxidation is the process that involves the reaction of a compound in the presence of oxygen. The…

Q: trehalose is a disacharide that can be obtained from fungi sea uchins and insects. acid hydrolysis…

A: From the given information, The hydrolysis of trehalose results the 2 D-glucose molecules, the…

Q: Zingerone, a spicy-sweet component of cooked ginger, can be converted to its protected TBDMS ether…

A: The first step is the abstraction of an acidic proton by a bulkier base like LDA (lithium…

Q: B. Give all possible and complete reaction for the following. Properly name the organic compound. 1.…

A: Given: organic compounds To find: complete reactions with proper name of the organic compound.

Q: Draw a stepwise mechanism for the following reaction, one step in thesynthesis of the…

A: A stepwise mechanism for the following reaction, one step in the synthesis of the…

Q: Reaction of X and phenylacetic acid forms an intermediate Y, which undergoes an intramolecular…

A:

Q: When A is treated with aqueous −OH, the major product is compound B, which undergoes ester…

A:

Q: Identify X, an intermediate that was converted to eletriptan (trade nameRelpax), a drug used to…

A: A modern and very important reaction in organic chemistry is the Heck reaction. In this reaction,…

Q: Identify F in the following reaction sequence. F was converted in several steps to the…

A: Firstly, the oxygen atom of the -OH group will attack the sulfur atom of methanesulfonyl chloride…

Q: D is an intermediate in the synthesis of rosiglitazone (trade name Avandia), a drug used to treat…

A: Body cells secrete many hormones which balance a person's metabolism. Hormones are basically…

Q: Draw structures for A, B, and C in the following reaction sequence and identify the process that…

A: Step 1 - When but-2-en-1-ol reacts with acetyl chloride in the presence of pyridine to form…

Q: Choose the product that is expected when the β-pyranose form of compound A is treated with excess…

A:

Q: d-Glucuronic acid is found widely in plants and animals. One of its functions is to detoxify…

A: Given: To determine the structure of the glucuronide formed by the reaction of beta-d-glucuronic…

Q: D is an intermediate in the synthesis of rosiglitazone (trade name Avandia), a drug used for type 2…

A: The given compound D can be prepared by nucleophilic substitution of alcohol and alkyl halide in…

Q: A D-aldopentose A is oxidized to an optically inactive aldaric acid with HNO3. A is formed by the…

A: solution;-

Q: The analgesic naproxen can be prepared by a stepwise reaction sequence from ester A. Using enolate…

A: To find: The reagents which are required to convert compound A to naproxen. Structure of the each…

Q: Reaction of X and phenylacetic acid forms an intermediate Y, which undergoes an intramolecular…

A: The structure of Y is as follows, In given reaction, the base abstracts the acidic proton from…

Q: Give a concise svnthesis for the molecules if they start from a benzene. a. F- -Br b. Но. OH C.

A:

Q: When A is treated with aqueous −OH, the major product is compound B, which undergoes ester…

A: The mechanism has to be given for the conversion of A to B.

Q: Devise a synthesis of attached compound from CH3CH2OH as the onlyorganic starting material; that is,…

A:

Q: OCH3

A: Here i have shown complete synthesis

Q: Devise a synthesis of CH3CH2CH2CHO from two-carbon starting materials. Draw both the retrosynthesis…

A:

Q: (a) Explain why phentermine [PhCH2C(CH3)2NH2] can’t be made by a reductive amination reaction.(b)…

A: (a)The structure of phentermine is given below.

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.