Answered: OH HNO2 „NH2 N H2NN `NH2 OH…

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OH HNO2 „NH2 N H2NN `NH2 OH 4,5-diaminopyrimidines 4-hydroxypyrazolo(3,4-d)pyrimidine aka: Allopurinol

Chemistry & Chemical Reactivity

10th Edition

ISBN:9781337399074

Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Chapter23: Carbon: Not Just Another Element

Section: Chapter Questions

Problem 52PS

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Question

please explain the steps in the following synthesis, what is the hno2 doing to cause allopurinol? what is being done to the 4,5-diaminopyrimidine? thank you!

OH
HNO2
„NH2
N
H2N
H2NN
`NH2
OH
4,5-diaminopyrimidines
4-hydroxypyrazolo(3,4-d)pyrimidine
aka: Allopurinol

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