ОН triosephosphate isomerase 2-0,PO. HO dihydroxyacetone phosphate H 2-0,PO. glyceraldehyde-3-phosphate
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Triosephosphate isomerase (TIM) catalyzes the conversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate. The enzyme’s catalytic groups are Glu 165 and His 95. In the first step of the reaction, these catalytic groups function as a general-base and a general-acid catalyst, respectively. Propose a mechanism for the reaction.
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- Phosphorylation of phosphatidylinositol yieldsa) Phosphatidylinositol 4, 5-biphosphateb) Phosphatidylinositol 3, 5-biphosphatec) Phosphatidylinositol 3, 4-biphosphated) Phosphatidylinositol 5, 6-biphosphateIsoform of Lactate dehydrogenase LDHWhich of these enzymes is needed to maintain a steady pool of methylene THF used in pyrimidine synthesis and cancer cells proliferation? Group of answer choices Phosphoglyceratedehydrogenase Glyceraldehydegehydrogenase Glycine decarboxylase Thymidylatesynthase
- Triacylglycerols in adipose tissue do not enter the bloodstream as triacyglycerolsexplainTrue or False a. Branching decreases the solubility of glycogen. True False b. The branching enzyme forms the α-1,6 linkage in glycogen. TrueFalseC17H29COOH linolenic acid non-saponifiable ω-3 fatty acid All are correct
- True or False c. Glycogen synthase catalyzes the synthesis of α-1,6 linkages. True False d. The activated form of glucose is added to the non-reducing end of glycogen molecules. True FalseCHOOSE THE CORRECT LETTER What type of reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase?A.phosphorylationB.reductionC. isomerizationD. oxidationFill in the blanks and explain the relationship between the paired words/phrases a. methotrexate: dihydrofolate reductase; ___________: thymidylate synthase b. __________: aspartate; purine: glycine
- reaction of glyceraldehyde-3-phosphate to form dihydroxyacetone phosphateCHOOSE THE CORRECT LETTER What type of reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase?A.oxidationB. reductionC. phosphorylationD. isomerizationIndividuals with inadequate tyrosine metabolism are oftenlight-sensitive and easily develop severe cases of sunburn.Explain. [Hint: The skin pigment melanin is derived froml-DOPA.]