Pathway analysis: Link the protein names to the correct statements by interrogating the depicted pathway.Options:A.RTK Receptor Threonine KinaseB.GEF Guanidine Exchange FactorC.PLC Phospholipase CD.GAP GTPase Activating ProteinE.GαiF.Raf Rapidly Accelerated FibrosarcomaG.PAK1 p21 Activated KinaseH.WASP Wiscott Aldrich syndrome proteinI.RTK Receptor Tyrosine KinaseJ.GPCR G-protein Coupled ReceptorK.Steroid ReceptorL.PhosphataseM.MEK1 (Mitogen-Activated Protein) Kinase/ERK (Extracellular Signal-Regulated Kinase) Kinase 1N.AC Adenylyl cyclaseO.IP3R IP3 ReceptorP.ERK1/2 Extracellular Signal-Regulated Kinase CHEMOKINE SIGNALING PATHWAYEosinophilNeutrophilMacrophageT lymphocyteCytokine-cytokine receptorinteractionchemokinechemkireR04062 8/24/20(c) Kanehisa Laboratories+pACGaiGByJAK2/3GagPKACAMPGRKB-arrestin1Receptor internalization* SrcPLC+pJak-STAT signalingpathway+pShcClass IAPI3KPI3KClass IB+p+p +p*FAKIP3DAGGRB2+pPIP3ItkPyk2CaSTAT+p+pSOSP-Rex1DOCK2ELMO1VavMAPK signalingpathwayRafRasPKCAktPaxillinp130CasCrkCalDAG-GEF1RasGRP2RaplPKCIKK+pBAD+P GSK3RacTiamlPar3PKCC✔Cdc42Pyk2p47phoxNADPH oxidaseMEK1ERK1/2FOXONFkB++pIKB|↓Ubiquitin mediatedproteolysisPAK1+pWASPRhoAFAK p130CasCrk PaxillinROCKCytokine productionCellular growth and differentiation.Cell survivalDNA MigrationApoptosisLeukocyte transendotherialmigrationMigrationChemotaxisCellular shape changesMete stasisDegranulationROS productionRegulation ofac tin cytoskeletonDegranulationNO inductionMigrationROS production ✓ What type of protein is the chemokine receptor?✓ TIAM acts as what type of regulator on Rac?✓ Loss or inactivation of which protein will lead toincreased cAMP (cyclic AMP)?✓ Which protein in this diagram is responsible for actinnucleation?✓ Which protein not shown in this diagram is directlyresponsible for the Calcium release in the cell?Which protein is designated as a MAPKK in thisdiagram?

No process within life forms are more intricated than the interconnected signal transduction…

Pathway analysis: Link the protein names to the correct statements by interrogating the depicted pathway. Options: A. RTK Receptor Threonine Kinase B. GEF Guanidine Exchange Factor C. PLC Phospholipase C D. GAP GTPase Activating Protein E. Gαi F. Raf Rapidly Accelerated Fibrosarcoma G. PAK1 p21 Activated Kinase H. WASP Wiscott Aldrich syndrome protein I. RTK Receptor Tyrosine Kinase J. GPCR G-protein Coupled Receptor K. Steroid Receptor L. Phosphatase M. MEK1 (Mitogen-Activated Protein) Kinase/ERK (Extracellular Signal-Regulated Kinase) Kinase 1 N. AC Adenylyl cyclase O. IP3R IP3 Receptor P. ERK1/2 Extracellular Signal-Regulated Kinase

Pathway analysis: Link the protein names to the correct statements by interrogating the depicted pathway. Options: A. RTK Receptor Threonine Kinase B. GEF Guanidine Exchange Factor C. PLC Phospholipase C D. GAP GTPase Activating Protein E. Gαi F. Raf Rapidly Accelerated Fibrosarcoma G. PAK1 p21 Activated Kinase H. WASP Wiscott Aldrich syndrome protein I. RTK Receptor Tyrosine Kinase J. GPCR G-protein Coupled Receptor K. Steroid Receptor L. Phosphatase M. MEK1 (Mitogen-Activated Protein) Kinase/ERK (Extracellular Signal-Regulated Kinase) Kinase 1 N. AC Adenylyl cyclase O. IP3R IP3 Receptor P. ERK1/2 Extracellular Signal-Regulated Kinase

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 12RQ: Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway...

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A.	RTK Receptor Threonine Kinase
B.	GEF Guanidine Exchange Factor
C.	PLC Phospholipase C
D.	GAP GTPase Activating Protein
E.	Gαi
F.	Raf Rapidly Accelerated Fibrosarcoma
G.	PAK1 p21 Activated Kinase
H.	WASP Wiscott Aldrich syndrome protein
I.	RTK Receptor Tyrosine Kinase
J.	GPCR G-protein Coupled Receptor
K.	Steroid Receptor
L.	Phosphatase
M.	MEK1 (Mitogen-Activated Protein) Kinase/ERK (Extracellular Signal-Regulated Kinase) Kinase 1
N.	AC Adenylyl cyclase
O.	IP3R IP3 Receptor
P.	ERK1/2 Extracellular Signal-Regulated Kinase