Ph H,O Ph. The final step in the Edman degradation is the acid-catalyzed rearrangement of the ATZ derivative to the PTH derivative Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Arrow-pushing Instructions Ph ỘH2 0-H :A R H-A Hö --R H. H.

Q: Which of the structures A through D is an intermediate in the synthesis of N-methyl phthalimide (2)…

A: In the given reaction CH3NH2 (methyl amine ) acts as like nucleophile, which attacks on anyhdride…

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Q: CyHN ch is worth 10 por intermediate #2 from intermediate #1 and for intermediate #3 going to the…

A: DCC is used for coupling of carboxylic acid and amine.

Q: Propose synthesis and show all intermediates for questions 3-4 HO H2N For #5 complete the rxn…

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Q: 4 Design the synthe tic route: NOz

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Q: draw PLP-dependent mechanisms for this reaction. General acids/bases may be involved as needed

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Q: 4. For each of the following proposed sequences (I-III): (a) determine if the synthetic route is…

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Q: HO2C n-BuLi, CO2 H H Me.,, THE Ме., -78 °C Me Me Me Me

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Q: 5. Among many of the drugs studied for the treatment of cancer is the carboxamide derivative Poly…

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Q: indozolin(i) from CH2COOC2H5 N OH

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Q: Explain the observed stereo-selectivity in the formation of product using Felkin-Anh model. (c) Ph.…

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Q: Alkene 14.1 was reacted with Br, as shown in Figure 14. A 1:1 ratio of products 14.2 and 14.3 was…

A: Bromonium cation is an three membered ring of the bromine where bromine is positively charged. And…

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A: Acids are proton donor whereas bases are proton acceptor.

Q: Amino acids contain reactive functional groups that need to be protected in synthesis. Draw the…

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Q: Scheme below shows the retrosynthesis analysis of 2-bromo-4-nitroaniline via Functional group…

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Q: k* КОН, МеОН 0 °C, 1 h RT, 1 h 0 °C, 12 h MeCOCI (3 equiv) K* МеОн (2.4 М) 0 °C, 30 min Room Temp.,…

A: A condensation reaction is a combination of two or more molecules to give a single molecule with the…

Q: Identify the compounds in Figure 7 that are an anhydride, amide, acyl chloride, and ester. Ph Ph Ph…

A: Anhydrides, amides, acyl chlorides and esters all are derivatives of acids.

Q: Complete the following synthesis route indicating the structures that are missing. .CI H2 Pd/C SnCl4…

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Q: Consider the -CH3 group and describe its directing properties in electrophilic aromatic…

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Q: H, а) OH H2S04 MgBr 1. BrMg" b) 2. НЗО OH но

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A: Our desired product in the given retrosynthesis reaction is 2-bromo-4-nitroaniline.

Q: Page 3 - for the following reaction. Page | 2 3. Complete the following synthetic pathways using…

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Q: 3. Show the complete mechanism for the reaction below. NH2 H2N-NH2 cat. HCI the pH of imine…

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Q: Show a detailed mechanism for the coupling of N-acetyl-L-proline to L-ValOBn using (a) DCC/HOBT

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Q: H b. . . C. d. i Hlor e. f. 2 H + H3C-C=N 1) NaOCzHg/C,H5OH 2) H₂O/H* NaOC₂H5 base & OH C2H5OH OH…

A: We have to draw the structure of the given products.

Q: What is the product from the sequenceoreactions depicted below?

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Q: O 1. CH3CH₂MgBr 2. H₂O

A: In the above given reaction grignard reagent (ethyl magnesiumbromide) reacts with ketone then workup…

Q: 10. Provide the product(s) based on the flow of electrons below: CH, + H-CI INTERMEDIATE cr

A: It is an example of electrophilic addition reaction

Q: Q6 Butryic Acid + Trimethylamine The following equation describes the reaction of butyric acid with…

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Q: онон CHI H* но OH Et;N EIOH Meo OMe Meo OMe Meo OMe Meo- Meo OMe A Meo- OMe mOEt OMe Eto OEt EIo OEt…

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Q: Which steps below would NOT be present in a Fischer esterification mechanism? LOH HO H. i. он : ОН…

A: Mechanism for Fischer esterification is goven below

Q: Amino acids contain reactive functional groups that need to be protected in synthesis. Draw the…

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Q: What is the outcome of the reaction sequence shown in the box? 1. Base 2. Allylbromide H3CO 3. НСІ,…

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Q: Note the major differences between the IR of the starting material(vanillin acetate) and the product…

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Q: Please show me the mechanism for O3+2-methyl-2-butene, stoping at the ozonide?

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Q: Construct a 9-point cycle that has a carboxylic acid and an ene as functional group. Name by IUPAC…

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Q: NV) Predict the products. cenade eurite 1. Mechanism ci mechandsome NH2NH2 Cao консаг

A: Aldehydes and ketones when heated with hydrazine and KOH give alkanes. This reduction is known as…

Q: Synthesis of Dilantin by Muli-Step Synthesis Part 4- Ureabenzil Condensation Table of Reagents…

A: The solution is given in the following steps :

Q: In the reaction below, the hydroxide ion serves as the: CH3CH₂C O Base o Nucleophile O Leaving Group…

A: The given reaction is  an example of nucleophilic substitution reaction. One nucleophile substitutes…

Q: HN- H. CO-H. -Zn2+ NH2 N. N. HO 4 N.

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Q: //sduu Questio Draw the products of the two step reaction sequence shown below. Ignore inorganic…

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