Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase converts DAG to phosphatidate.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question

URGENT!!!PLZ HELP

Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase
converts DAG to phosphatidate.
CH2-O-
CH
CH₂
phosphatidic acid
phosphatase
H₂O
P₁
ADP ATP
diacylglycerol
kinase
Concentration will increase
CH2-O-
TE
R₂
CH
CH₂-OH
-R₁
Consider the effect of a mutation in the PAP gene on triacylglycerol and phospholipid synthesis. Classify each lipid based on
whether its concentration will increase or decrease if the gene for PAP is underexpressed.
Concentration will decrease
Transcribed Image Text:Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase converts DAG to phosphatidate. CH2-O- CH CH₂ phosphatidic acid phosphatase H₂O P₁ ADP ATP diacylglycerol kinase Concentration will increase CH2-O- TE R₂ CH CH₂-OH -R₁ Consider the effect of a mutation in the PAP gene on triacylglycerol and phospholipid synthesis. Classify each lipid based on whether its concentration will increase or decrease if the gene for PAP is underexpressed. Concentration will decrease
phospholipids generated from CDP-DAG
and a polar head group
phospholipids generated from DAG
and activated head groups
R2–CO—CH
CH, O
R₂-C-O-CH
Answer Bank
||
CH₂0-C-R₁
ofo
CH₂-O-F
-O-8-R₁
0
CH₂-O-P-O-CH₂-CH-COO™
+
0
NH3
I
triacylglycerols
O
CH₂-O-C-R₁
R2-8-0-CH
CH2O
o=d-0
O
H OH
OH
H
OH HO
H
H
H
OH
Transcribed Image Text:phospholipids generated from CDP-DAG and a polar head group phospholipids generated from DAG and activated head groups R2–CO—CH CH, O R₂-C-O-CH Answer Bank || CH₂0-C-R₁ ofo CH₂-O-F -O-8-R₁ 0 CH₂-O-P-O-CH₂-CH-COO™ + 0 NH3 I triacylglycerols O CH₂-O-C-R₁ R2-8-0-CH CH2O o=d-0 O H OH OH H OH HO H H H OH
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps with 4 images

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON