Predict the major product(s) of the following reaction sequences. 1. I2, NaOH (excess reagents), CH3 2. H;0* F 1. LDA 2. OEt (Hint: Here the enolate acts as a nucleophile in an addition-elimination mechanism with the ester)

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter25: Enolate & Enol Nucleophiles
Section: Chapter Questions
Problem 18E
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Predict the major product(s) of the following reaction sequences.
1. I,, NaOH (excess reagents),
CH3
2. H;O*
F1
1. LDA
2.
OEt
(Hint: Here the enolate acts
as a nucleophile in an addition-elimination
mechanism with the ester)
Transcribed Image Text:Predict the major product(s) of the following reaction sequences. 1. I,, NaOH (excess reagents), CH3 2. H;O* F1 1. LDA 2. OEt (Hint: Here the enolate acts as a nucleophile in an addition-elimination mechanism with the ester)
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