Provide at least two (2) biological processes with which PHOSPHOLIPASE C FROM BACILLUS CEREUS is associated with and briefly summarize its role
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Provide at least two (2) biological processes with which PHOSPHOLIPASE C FROM BACILLUS CEREUS is associated with and briefly summarize its role
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- The metabolic precursor for the production of most eicosanoids isNeuraminidase (NA) catalyzes a hydrolysis of the glycosidic linkages of sialic acids using a mechanism shown in Fig. (a). and Fig. (b) shows competitive inhibitors of NA Considering the mechanism of NA, why do zanamivir and oseltamivir inhibit NA so potently?Compare and contrast the c4 pathway and the malate–aspartate shuttle in bullet format, meaning list the similarities and differences.
- . List and describe the components of the cytochrome P450electron transport system. What is the role of eachcomponent?Using the ActiveModel for phosphofructokinase (Trypanosoma), describe the difference between the APO1, AP02, and holoenzyme conformations.What is the catalytic triad on chymotrypsin? Detail its importance.
- Saccharomyces cerevisiae is used in the production of wine and beer, while Lactobacillus acidophilus is used in making yogurt. Explain why each is biochemically suited to the manufacturing of each of these products.Give a possible set of bacterial factors (or lack thereof) and what properties they have that would explain an increase in the 50% inhibitory concentration for tetracycline by 1,000-fold in an organism.Outline the steps involved in the production of malonylCoA from acetyl-CoA.
- The major enzymatic defense against oxidative stress is provided by superoxide dismutase, glutathione, peroxidase, peroxiredoxin, and _____________The following data, presented by G. Bowes and W. L. Ogre in J. Biol. Chem. (1972) 247:2171–2176, describe the relative rates of incorporation of CO2 by Rubisco under N2 and under pure O2. Decide whether O2 is a competitive or uncompetitive inhibitor.What beneficial properties of rasagiline make it useful for the treatment of Alzheimer’s disease?