Pyruvate kinase, a glycolysis enzyme

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 20P: Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have...
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Oxygen is transported from your lungs to tissues throughout your body by red blood
cells. Approximately 2.4 million new red blood cells are produced per second in
human adults. The functional lifetime of a red blood cell is about 100-120 days,
during which time the red blood cells are continually moved by the blood flow.
Which of the following enzyme deficiencies could possibly cause hemolytic anemia
due to breakdown and loss of red blood cells?
Isocitrate dehydrogenase, a Krebs cycle enzyme
Pyruvate kinase, a glycolysis enzyme
Succinyl-CoA synthetase, a Krebs cycle enzyme
Ubiquinone oxidoreductase, complex I of the electron transport chain
Transcribed Image Text:Oxygen is transported from your lungs to tissues throughout your body by red blood cells. Approximately 2.4 million new red blood cells are produced per second in human adults. The functional lifetime of a red blood cell is about 100-120 days, during which time the red blood cells are continually moved by the blood flow. Which of the following enzyme deficiencies could possibly cause hemolytic anemia due to breakdown and loss of red blood cells? Isocitrate dehydrogenase, a Krebs cycle enzyme Pyruvate kinase, a glycolysis enzyme Succinyl-CoA synthetase, a Krebs cycle enzyme Ubiquinone oxidoreductase, complex I of the electron transport chain
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