Question 1. Enzymes, proteins and deoxyribonucleic acid (DNA) are important macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA reproduction. biological e) Michaelis - Menten Kinetics model explains how reaction rates are depending on the concentration of enzyme and substrate. i. What is meant by the saturation of enzyme? A decrement in enzyme activity is known as enzyme inhibition. Based on normal enzyme activity, explain the enzyme kinetics for competitive inhibition and noncompetitive inhibition, as shown in Figure 1. ii. Normal enzyme Competitive inhibitor Noncompetitive inhibitor Substrate concentration Figure 1: Enzyme inhibition f) What is the importance of cofactor in the enzyme activity? Give an example of a disease that is related with cofactors. Rate of reaction

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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Question 1.
Enzymes, proteins and deoxyribonucleic acid (DNA) are important biological
macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA
reproduction.
e) Michaelis - Menten Kinetics model explains how reaction rates are depending on the
concentration of enzyme and substrate.
i.
What is meant by the saturation of enzyme?
ii. A decrement in enzyme activity is known as enzyme inhibition. Based on normal
enzyme activity, explain the enzyme kinetics for competitive inhibition and
noncompetitive inhibition, as shown in Figure 1.
Normal
enzyme
Competitive inhibitor
Noncompetitive inhibitor
Substrate concentration
Figure 1: Enzyme inhibition
f) What is the importance of cofactor in the enzyme activity? Give an example of a disease
that is related with cofactors.
Rate of reaction
Transcribed Image Text:Question 1. Enzymes, proteins and deoxyribonucleic acid (DNA) are important biological macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA reproduction. e) Michaelis - Menten Kinetics model explains how reaction rates are depending on the concentration of enzyme and substrate. i. What is meant by the saturation of enzyme? ii. A decrement in enzyme activity is known as enzyme inhibition. Based on normal enzyme activity, explain the enzyme kinetics for competitive inhibition and noncompetitive inhibition, as shown in Figure 1. Normal enzyme Competitive inhibitor Noncompetitive inhibitor Substrate concentration Figure 1: Enzyme inhibition f) What is the importance of cofactor in the enzyme activity? Give an example of a disease that is related with cofactors. Rate of reaction
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