Select the phrases that accurately describe properties of the most common form of the DNA double helix. DNA contains equal amounts of adenine and thymine and equal amounts of cytosine and guanine. The nitrogenous bases are exposed to the solvent, whereas the sugar-phosphate backbone of each nucleotide strand is in the interior of the double helix. The phosphodiester bonds between nucleotide residues run in opposite directions in the two strands. Base pairs have a spacing of 3.4 Å. A helical turn consists of about 3.4 base pairs.
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- Using Figures 8.7 and 8.9 as a guide, draw a dinucleotide composed of C and A. Next to this, draw the complementary dinucleotide in an antiparallel fashion. Connect the dinucleotides with the appropriate hydrogen bonds. FIGURE 8.9 The two polynucleotide chains in DNA run in opposite directions. The left strand runs 5 to 3, and the right strand runs 3 to 5. The base sequences in each strand are complementary. An A in one strand pairs with a T in the other strand, and a C in one strand is paired with a G in the opposite strand. FIGURE 8.7 Nucleotides can be joined together to form chains caled polynucleotides. Polynucleotides are polar molecules with a 5 end (at the phosphate group) and a 3 end (at the sugar group). An RNA polynucleotide is shown at the left, and a DNA polynucleotide is shown at the right.Describe the structure and complementary base pairing of DNA.Match the following terms with their correct definition. The structure of double-standed DNA Hold the base pairs together and make up the rungs of the DNA double helix One strand of nucleotides running in the opposite direction of the other strand Consists of a phosphate, a sugar backbone, and a nitrogen base A-T and C-G base pairs Five-carbon sugar found in DNA Complementary base pairs Double helix Antiparallel Nucleotide Hydrogen bonds Deoxyribose sugar
- Match the following terms with their correct definition. The structure of double-standed DNA Hold the base pairs together and make up the rungs of the DNA double helix One strand of nucleotides running in the opposite direction of the other strand Consists of a phosphate, a sugar backbone, and a nitrogen base A-T and C-G base pairs Five-carbon sugar found in DNA Answer Complementary base pairs Answer Double helix Answer Antiparallel Answer Nucleotide Answer Hydrogen bonds Answer Deoxyribose sugarTabulate the differences of the various DNA conformations in terms of orientation, rise per base pair (bp), pitch per trun of helix and helix diameter.– Draw a DNA strand with 10 adenine bases followed by 10 cytosine bases. If that same strand bonded to a strand of 15 thymine bases and 5 guanine bases, how would the double helix shape vary from a typical DNA double helix? Explain why. Must draw picture of both strands that helps to illustrate your written answer – no credit for one without the other.
- Which statement correctly explains the chemical basis of Chargaff's rules? Specific purines and specific pyrimidines will always be found opposite each other in the two opposing DNA strands. The double-stranded DNA helix contains phosphodiester bonds linking the nucleotides together. The DNA strands are oriented in an antiparallel direction. Phosphate groups and deoxyribose form the outside backbone of the double stranded DNA molecule. Nucleotides are always composed of a pentose sugar, phosphate, and nitrogenous base.Consider an intact length of DNA consisting of 140 total nucleotides (70 nucleotides/strand), with 40 total adenine nitrogen bases. How many of each of the following molecules would be found in the length? MoleculeNumber Adenine40 Guanine___ Thymine___ Deoxyribose___ Uracil___ Phosphate Groups___ Ribose___ Cytosine___Indicate whether each of the following statements about the double-helix secondary structure of DNA is true or false. a. The two polynucleotide strands are complementary rather than identical. b. Bases present extend outward from the double helix. c. Covalent bonding occurs between the two polynucleotide strands. d. The two polynucleotide strands run in the 5′-to-3′ direction
- You are supplied with the following information about a DNA molecule: The molecular weight of a typical nucleotide is 660 Da. The linear density of double stranded DNA is 4 x 106 Da per micrometer. There are 10 base pairs in one complete turn of the double helix. Answer the following questions about a DNA molecule with a length of 3.3 micrometer and a base composition which contains 20% of the base adenine (A). (a) How many phosphor atoms are present in this DNA molecule?(b) How many full turns of the DNA helix are there in this molecule?(c) What is the percentage of guanine bases in the DNA molecule?(d) How many hydrogen bonds are there in the molecule?(e) How many phosphodiester bonds are there in the molecule?( f ) What is the length in basepairs of a DNA molecule that contains 606 full turns of the double helix?The compound known as nitrous acid is a reactive chemical that replaces amino groups (−− NH2) with keto groups (== O). When nitrous acid reacts with the bases in DNA, it can change cytosine to uracil and change adenine to hypoxanthine. A DNA double helix has the following sequence: TTGGATGCTGG AACCTACGACC A. What would be the sequence of this double helix immediately after reaction with nitrous acid? Let the letter H represent hypoxanthine and U represent uracil. B. Let’s suppose this DNA was treated with nitrous acid. The nitrous acid was then removed, and the DNA was replicated for two generations. What would be the sequences of the DNA products after the DNA had replicated twice? Your answer should contain the sequences of four double helices. Note: During DNA replication, uracil hydrogen bonds with adenine, and hypoxanthine hydrogen bonds with cytosine.What describes or designates the 3' end of a DNA strand? a. an available hydroxyl group on the 5th carbon of a deoxyribose of a terminal nucleotide b. an available phosphate group on the 3rd carbon of a deoxyribose of a terminal nucleotide c. an available hydroxyl group on the 3rd carbon of a deoxyribose of a terminal nucleotide d. an available hydroxyl group on the 2nd carbon of a deoxyribose of a terminal nucleotide