TABLE 5.2 Examples of Mammalian Genes That Are Imprinted* Allele Gene Expressed Function WT1 Maternal Wilms tumor-suppressor gene; suppresses cell growth Insulin; hormone involved in cell growth and metabolism INS Paternal Igf2 Paternal Insulin-like growth factor Il; similar to insulin Igf2R Maternal Receptor for insulin-like growth factor II UBЕЗА Maternal Regulates protein degradation; involved in Angelman syndrome Splicing factor; involved in Prader-Willi syndrome SNRPN Paternal Gabrb Maternal Neurotransmitter receptor "Researchers estimate that approximately 1-2% of human genes are subjected to genomic imprinting, but only about 100 have actually been demonstrated to be imprinted.
TABLE 5.2 Examples of Mammalian Genes That Are Imprinted* Allele Gene Expressed Function WT1 Maternal Wilms tumor-suppressor gene; suppresses cell growth Insulin; hormone involved in cell growth and metabolism INS Paternal Igf2 Paternal Insulin-like growth factor Il; similar to insulin Igf2R Maternal Receptor for insulin-like growth factor II UBЕЗА Maternal Regulates protein degradation; involved in Angelman syndrome Splicing factor; involved in Prader-Willi syndrome SNRPN Paternal Gabrb Maternal Neurotransmitter receptor "Researchers estimate that approximately 1-2% of human genes are subjected to genomic imprinting, but only about 100 have actually been demonstrated to be imprinted.
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter17: Developmental Genetics
Section: Chapter Questions
Problem 8TYU: Which of the following statements about cancer is false? (a) oncogenes arise from mutations in...
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On the left side of this figure, explain why the offspring
does not have Prader-Willi syndrome but does have Angelman syndrome
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