The amino acid histidine has ionizable groups with p?a values of 1.8, 6.0, and 9.2, as shown. A biochemist makes up 95 mL of a 0.15 M solution of histidine at a pH of 5.3. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

The amino acid histidine has ionizable groups with p?a values of 1.8, 6.0, and 9.2, as shown. A biochemist makes up 95 mL of a 0.15 M solution of histidine at a pH of 5.3. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

Body Structures & Functions

12th Edition

ISBN:9781285695495

Author:Scott

Publisher:Scott

Chapter1: Introduction To The Structural Units

Section: Chapter Questions

Problem 3FIB

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Question

The amino acid histidine has ionizable groups with p?a values of 1.8, 6.0, and 9.2, as shown.

A biochemist makes up 95 mL of a 0.15 M solution of histidine at a pH of 5.3. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

COOH
H₂N-CH
CH ₂
H
CH
lonizable -COOH
group
COO-
H₂N-CH
T
1.8
pk₁
CH2
COO-
H
CH
-HisH+
COO™
H₂N-CH
6.0
pk₂
CH, H
-His
CH
-NH
COO™
H₂N-CH
I
CH₂ H
9.2
pk3
-NH₂
CH

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