The catalytic efficiency of many enzymes depends on pH.Chymotrypsin shows a maximum value of kaKM at pH 8. Detailedanalysis shows that kat increases rapidly between pH 6 and 7 andremains constant at higher pH. KM increases rapidly between pH 8and 10. Suggest explanations for these observations.

Chymotrypsin is a protelytic enzyme acting in the digestive system of many organisms. It facilitates…

Answered: The catalytic efficiency of many…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter17: Metabolism: An Overview

Section: Chapter Questions

Problem 6P: Why Do Anabolic and Catabolic Pathways Differ? Why is the pathway for the biosynthesis of a...

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The catalytic efficiency of many enzymes depends on pH. Chymotrypsin shows a maximum value of kaKM at pH 8. Detailed analysis shows that kat increases rapidly between pH 6 and 7 and remains constant at higher pH. KM increases rapidly between pH 8 and 10. Suggest explanations for these observations.