The enzyme urease catalyses the reaction in which urea is hydrolysed to ammonia and carbon dioxide. The half-life of urea in the pseudofirst-order reaction for a certain amount of urease doubles when the temperature islowered from 20 oC to 10 oC and the Michaelis constant is largely unchanged. What is the activation energy of the reaction?

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
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Chapter11: Chemical Kinetics: Rates Of Reactions
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Problem 80QRT: When enzymes are present at very low concentration, their effect on reaction rate can be described...
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The enzyme urease catalyses the reaction in which urea is hydrolysed to ammonia and carbon dioxide. The half-life of urea in the pseudofirst-order reaction for a certain amount of urease doubles when the temperature is
lowered from 20 oC to 10 oC and the Michaelis constant is largely unchanged. What is the activation energy of the reaction?

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