The function of the PTEN phosphatase in the Pl-3 kinase signaling pathway. The loss of function mutation in PTEN promotes cancer. The prediction of the constitutively active PTEN effect on cell growth and survival.

The function of the PTEN phosphatase in the Pl-3 kinase signaling pathway. The loss of function mutation in PTEN promotes cancer. The prediction of the constitutively active PTEN effect on cell growth and survival.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter32: The Reception And Transmission Of Extracellular Information

Section: Chapter Questions

Problem 2P

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Concept explainers

Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.

Question

The function of the PTEN phosphatase in the Pl-3
kinase signaling pathway. The loss of function
mutation in PTEN promotes cancer. The prediction of
the constitutively active PTEN effect on cell growth
and survival.

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