Cotranscriptional processing of RNA (a) Capping Transcription start site Cap CTD Capping enzymes (b) Splicing CTD RNA splicing 5 machinery (c) Cleavage and polyadenylation Poly(A) tail added (d) Final product - Poly(A) tail FIGURE 8-13 Cotranscriptional processing of RNA is coordinated by the carboxyl tal domain (CTD) of the B subunit of RNA polymerase II Reversible phosphorylation of the amino acids of the CTD (indicated by the P's) creates binding sites for the different processing enzymes and factors required for (a) capping, (b) splicing, and (c) cleavage and polyadenylation.

Cotranscriptional processing of RNA (a) Capping Transcription start site Cap CTD Capping enzymes (b) Splicing CTD RNA splicing 5 machinery (c) Cleavage and polyadenylation Poly(A) tail added (d) Final product - Poly(A) tail FIGURE 8-13 Cotranscriptional processing of RNA is coordinated by the carboxyl tal domain (CTD) of the B subunit of RNA polymerase II Reversible phosphorylation of the amino acids of the CTD (indicated by the P's) creates binding sites for the different processing enzymes and factors required for (a) capping, (b) splicing, and (c) cleavage and polyadenylation.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter30: Protein Synthesis

Section: Chapter Questions

Problem 12P

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