The key to epigenetic regulation is ________. a. controlling accessibility to transcription factors and RNA polymerase binding b. biochemical modification of binding factors c. physical modification of the DNA
Q: Using coat color in mice and the development of female honeybees as examples, explain how dietary…
A: The inheritance of phenotypic characteristics without any changes at the genetic level is called…
Q: Genetic instability in the form of point mutations, chromosome rearrangements, and epigenetic…
A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…
Q: Which of the following mutations could be appropriately describedas a position effect?A. A point…
A: The mutation is caused due to alteration occurred in the gene sequence due to either environmental…
Q: My Avya mouse is brownish because a) the CpG island with the transposon is unmethylated. b) it was…
A: Epigenetic systems that facilitate gene-environment interactions are involved in the ability of…
Q: transcriptional repressor leading to decreased gene expression. a. chromatin remodelling complex…
A: Transcriptional repressors are the molecules that block/inhibit gene expression. They directly act…
Q: Suggest a direct experiment to prove that p53 binding at gene promoters affects the level of gene…
A: p53 is a protein responsible for tumor suppression and helps in regulation of the overgrowth of…
Q: Where do enhancers bind? Are enhancers gene specific
A:
Q: A mutation occurs in a gene, resulting in it being expressed at the wrong time during development.…
A: The mutation refers to change the sequence of nucleotide in a gene.
Q: List and briefly describe five types of molecular mechanisms thatmay underlie epigenetic gene…
A: A gene is a stretch of nucleotides present in the DNA. DNA or deoxyribonucleic acid is a polymer of…
Q: Also, describe what happens when a nonsense mutation is introduced into the gene encoding…
A: Mutations- Change in the sequence & structure of genetic material. Mutation causing agents are…
Q: Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription…
A: The transcriptional process of genes has some differences in prokaryotic cells and eukaryotic cells.…
Q: Which of the following combinations will cause transcription to be activated? a. A repressor plus an…
A: The transcription is a process through which information in the DNA molecule is transcribed into…
Q: Describe the molecular steps by which polycomb groups cause epigenetic gene silencing.
A: Polycomb group (PcG) proteins are members of the protein family that were initially discovered in…
Q: Gene expression in bacteria is controlled by the operon model. a) Why is the operon model…
A: BASIC INFORMATION OPERON MODEL This model of gene regulation was put forward by Francis Jacob and…
Q: What is the advantage of using the neo gene to disrupt the function of a gene in knockout mice? a.…
A: Answer- Neo gene is amino 3'- glycosyl phosphotransferase which acts as a selectable marker in…
Q: 1. Epigenetic marks refer to modifications to DNA and proteins that in tum regulate gene expression.…
A: Different macromolecules are present in humans. They include carbohydrates, lipids, proteins, and…
Q: statement is true. Both statements are false. 1. Epigenetics does not consider how exposure to…
A: Epigenetics is the study of how your behaviour and environment can influence how your genes…
Q: Insulators may exert their effect by a. acting as a barrier to changes in chromatin structure. b.…
A: Insulator sequences are the cis-regulatory DNA sequences that protect the gene from inappropriate…
Q: Some antibiotics, such as rifampin, interfere with the function of RNA polymerase. What biological…
A: Antibiotic is a substance released by any microorganism against other microorganism. These…
Q: How is transcription directly controlled in eukaryotic cells? a. through the use of phosphorylation…
A: Transcription refers to a process that transcribes the DNA molecule into a molecule called RNA which…
Q: The “domain-swapping” experiment that grafts the Gal4 DNA-binding domain to the LexA activation…
A: The ans is option C.
Q: The molecular mechanisms that underlie epigenetics include which of the following? (select all that…
A: The expression of genes can be controlled by different mechanisms. The epigenetic modification is…
Q: The functioning of enhancers is an example of(A) a eukaryotic equivalent of prokaryotic promoter…
A: Enhancer refers to a short region of DNA. It increases the process of transcription of a particular…
Q: Specific transcription factors in eukaryotes interact with enhancers, which may be a long distance…
A: Transcription is the process by which mRNA is transcribed from double-stranded DNA. The core enzyme…
Q: What have epigenetic monozygotic twin studies proven? A. Twins have identical epigenomes because…
A: The term epigenetics means something that occurs due to a non-genetic influence on the expression of…
Q: Which of the following will increase the rate of transcription? a. Activation of a transcriptional…
A: Transcription is defined as the synthesis of RNA molecules using DNA as a template that results in…
Q: (a) Did deletion of any of the possible control elements cause areduction in reporter gene…
A: Gene expression is a process by which the genes are turned on to form RNA and proteins. DNA…
Q: Which of the following does not accurately describe eukaryotic transcriptional factors? a. Changes…
A: Introduction Transcription factors are the proteins that specifically are involved in the…
Q: Which of the following is an explanation for how there can be differential gene expression…
A: Ans-C) There are unique combinations of transcription factors in different tissues of the organism…
Q: Your investors are concerned that the GasP protein might not be sufficiently produced under normal…
A: Answer a. As the transcription of GasP protein has been 'triggered' by some chemical (abiotic…
Q: chromodomains? a) b
A: Answer Chromodomain bind methylated histone tail and are associated with repression.
Q: You wish to determine which genes are aberrantly expressed in a certain type of cancer. How would…
A: Cancer is a disease of uncontrolled gene expression. It is a proliferative disease as it can induce…
Q: What would happen to an insulator (for example, like the ICR between the Igf2 and H19 genes) if it…
A: Insulator are cis-regulatory elements. Upon binding by insulator binding proteins, they prevent…
Q: Which ONE of the following is TRUE concerning the so‐called Philadelphia chromosome? Select one:…
A: Chromosomal deletion is simply deletion of the part of the chromosome. Chromosomal inversion is a…
Q: Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b.…
A: Deoxyribonucleic acid (DNA) is a double-stranded molecule. DNA replication is the process by which…
Q: How do I draw the sequence and explain the process for each step? Draw the sequence of molecular…
A: In the nucleus, the STAT dimers localise and bind to specific DNA targets and induce gene…
Q: Mutations in the CFTR gene result in cystic fibrosis in humans, a conditions in which abnormal…
A: Cystic fibrosis is a hereditary disorder that basically affects the digestive system and lungs of…
Q: Describe what would happen to the lac operon in a low-lactose environment and in a high lactose…
A: LacZ (encodes beta-galactosidase), lacY (permease), and lacA (trans-acetylase) are the three genes…
Q: How can methylation affect transcription? a. It may prevent the binding of regulatory transcription…
A: Introduction: DNA methylation, an epigenetic characteristic in eukaryotic organisms, is a process by…
Q: Which of the following will lead to epigenetic gen O a. A decrease in histone deacetylation. O b. An…
A: Epigenetic changes occur due to environmental changes in the surrounding atmosphere. Enzymes are…
Q: Cro protein expression and activity may be activated in a prophage by a)lysogenic dominance b)rapid…
A: Role of Cro protein: The host SOS response triggers the prophage induction by…
Q: In a recent study, scientists used gene editing to treat both sickle cell disease and…
A: Sickle cell disease and beta thalassemia are genetic disorders caused by errors in genes of…
Q: Suppose we take tissue samples from the kidney and the liver of a healthy individual. If we compare…
A: Genetic sequences or the genome of a cell is present in the nucleus and includes DNA molecule…
Q: 1. Where would the RNA polymerase II bind this piece of DNA = region B 2. What DNA sequence would…
A: 1. DNA polymerase 2 binds with the piece of DNA - B & A. Explanation - Region B is the - 80 CAAT…
Q: Outline the types of molecular changes that underlie epigeneticgene regulation.
A: Introduction Gene expression during the developmental phase can be regulated by several factors…
Q: A DNA mutation in which of the following part of a gene is likely to be most damaging to…
A: It is a multiple choice question.
Q: Arrange the events leading to the TURNING OFF of the structural genes. Write the capital letter…
A: An operon is essentially a gene regulatory system in which a collection of genes coding for…
Q: In one cell, gene C is expressed, whereas in another cell, geneC is inactive. After the cells are…
A: Epigenetics is defined as the study of heritable phenotypic changes but it does not change the DNA…
| a. | controlling accessibility to transcription factors and RNA polymerase binding | |
| b. | biochemical modification of binding factors | |
| c. | physical modification of the DNA |
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
- In one cell, gene C is expressed, whereas in another cell, geneC is inactive. After the cells are fused experimentally, both copiesof gene C are expressed. This observation could be explained bya. a cis-epigenetic mechanism.b. a trans-epigenetic mechanism.c. DNA methylation.d. both a and b.Post-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translationWhich of the following is NOT a description of an epigenetic modification? A. regulatory patterns that persisis in the absence of the original signal B. stable alterations in gene expression without changes to the underlying DNA sequence C. the persistence of gene expression patterns through cell division D. an intrinsic signal that triggers cell differentiation
- Which of the following is an example of epigenetic modulation? a) Ionization-induced DNA damage b) Single nucleotide polymorphism (SNP) c) Free-radical induced DNA damage d) Histone modifications of DNAEpigenetic marks regulate gene expression. Which epigenetic mark is NOT associated with positive gene expression? A. Histone acetylation B. Histone Methylation C. De-methylated DNA D. Methylated DNAWhich of the following is not a possible outcome of changing the epigenetic code? a) exposure of regulatory region b) binding of transcription factors c) altered gene expression d) repositioning of nucleosomes by polymerases
- Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA moleculesWhat are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequenceDefine Epigenetic changes. Are epigenetic changes the same thing as mutations? Explain why or why not.
- Epigenetic control of gene expressiona. is hereditary. c. adds methyl groups to cytosine.b. locks genes “ON.” d. Two of theseWhat strategy does a genetically encoded calcium indicator look like to allow fluorescence imaging of only one cell type in an acute slice of the brain? A.The use of fluorescent protein expression inhibitors in other cells B.The injection of a recombinant virus causing the death of other cells C.The use of a promoter specific to these cells D.Activation of membrane receptors specific to these cellsThe role of p53 in normal cells is toa. create cancer-blocking mutations.b. trigger unrestrained cell division.c. detect damaged DNA.d. splice exons together in the correct sequence.