Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA molecules
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Which of the following is not a major mechanism of epigenetic change?
a. DNA methylation
b. Alteration of a DNA base sequence in a promoter
c. Histone acetylation
d. Action of RNA molecules
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- Which of the following is an example of epigenetic modulation? a) Ionization-induced DNA damage b) Single nucleotide polymorphism (SNP) c) Free-radical induced DNA damage d) Histone modifications of DNAWhich of the following is NOT a description of an epigenetic modification? A. regulatory patterns that persisis in the absence of the original signal B. stable alterations in gene expression without changes to the underlying DNA sequence C. the persistence of gene expression patterns through cell division D. an intrinsic signal that triggers cell differentiationWhat are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequence
- Which of the following is not a possible outcome of changing the epigenetic code? a) exposure of regulatory region b) binding of transcription factors c) altered gene expression d) repositioning of nucleosomes by polymerasesThe key to epigenetic regulation is ________. a. controlling accessibility to transcription factors and RNA polymerase binding b. biochemical modification of binding factors c. physical modification of the DNAEpigenetic marks regulate gene expression. Which epigenetic mark is NOT associated with positive gene expression? A. Histone acetylation B. Histone Methylation C. De-methylated DNA D. Methylated DNA
- Define Epigenetic changes. Are epigenetic changes the same thing as mutations? Explain why or why not.Epigenetic changes in gene regulation are caused by _ _ _ _ _ _ _ a. missing nucleotides or chromosomes b. modifications to histones and the DNA, but not the nucleotide sequence itself c. mutations of the nucleotide sequencePost-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translation
- Epigenetic modification of gene expressiona. always inhibits gene transcription.b. always stimulates gene expression.c. is erased from the DNA following mitotic cell division.d. may sometimes be transmitted from generation to generation.A scientist does an experiment in which she removes the offspring of rats from their mother at birth and has her genetics students feed and rear the offspring. Assuming that the students do not lick and groom the baby rats as the mother rats normally do, what long-term behavioral and epigenetic effects would you expect to see in the rats when they grow up?Which of the following are examples of molecular changes thatcan have an epigenetic effect on gene expression?a. Chromatin remodelingb. Covalent histone modificationc. Localization of histone variantsd. DNA methylatione. Feedback loopsf. All of the above