True or False 1. There can be a quantitative determination of the degree of supercoiling in a DNA sample. 2. Topoisomerases can cut phosphodiester bonds and the DNA ligases will have to seal the nicks whenever there is a need to relieve the supercoiling. 3. Histone proteins are able to associate with DNA segments because of the anionic nature of the amino acids arg and lys.
True or False 1. There can be a quantitative determination of the degree of supercoiling in a DNA sample. 2. Topoisomerases can cut phosphodiester bonds and the DNA ligases will have to seal the nicks whenever there is a need to relieve the supercoiling. 3. Histone proteins are able to associate with DNA segments because of the anionic nature of the amino acids arg and lys.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 1P: Semiconservative or Conservative DNA Replication If 15N-Iabeled E. coli DNA has a density of 1.724...
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True or False
1. There can be a quantitative determination of the degree of supercoiling in a DNA sample.
2. Topoisomerases can cut phosphodiester bonds and the DNA ligases will have to seal the nicks whenever there is a need to relieve the supercoiling.
3. Histone proteins are able to associate with DNA segments because of the anionic nature of the amino acids arg and lys.
4. The supercoiled DNA can either be positively or negatively supercoiled.
5. The Sanger method of DNA sequencing follows the principle of complementarity just like in the replication process.
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