Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question
Hi, i dont understand the steps here. Could you rewrite this in a more simple manner so i could understand better. Thanks
"seaas
The aim of this experiment was investigating and determining the effect of the pH of a
solution on the distribution coefficient of a drug, in this case benzoic acid. In order to carry
out this investigation, a pre-prepared 0.001998 mol dm stock solution of benzoic acid in
ethyl acetate was used to prepare standard solutions of varying concentrations whose
absorbances were measured to produce a calibration plot. A biphasic liquid of stock solution
and pH 6.0 buffer was produced and the absorbance was then recorded and used to
calculate the distribution coefficient of benzoic acid at this pH. The orocess then repeated,
using pH 7.0 buffer.
nt 70 buffer sotution
Transcribed Image Text:"seaas The aim of this experiment was investigating and determining the effect of the pH of a solution on the distribution coefficient of a drug, in this case benzoic acid. In order to carry out this investigation, a pre-prepared 0.001998 mol dm stock solution of benzoic acid in ethyl acetate was used to prepare standard solutions of varying concentrations whose absorbances were measured to produce a calibration plot. A biphasic liquid of stock solution and pH 6.0 buffer was produced and the absorbance was then recorded and used to calculate the distribution coefficient of benzoic acid at this pH. The orocess then repeated, using pH 7.0 buffer. nt 70 buffer sotution
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Micelles and Biological Membranes
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY