Using the information below, calculate the percentage w/v of lidocaine (MM (234.34 g/mol) in Lignocaine Oral Topical Solution. Show your reasoning clearly and record your final answer to three significant figures.
Question 4
Using the information below, calculate the percentage w/v of lidocaine (MM (234.34 g/mol)
in Lignocaine Oral Topical Solution. Show your reasoning clearly and record your final
answer to three significant figures.
"Transfer an accurately measured volume of Oral Topical Solution,
equivalent to about 150 mg of lidocaine, to a 125 mL conical flask,
and protect from atmospheric moisture with a stopper fitted with a
tube containing silica gel. Add 20 mL of glacial acetic acid and 2 drops of
crystal violet TS. Titrate immediately with 0.1 M perchloric acid VS to a blue endpoint.
Perform a blank titration, and make the necessary correction."
Results:
.
Amount of topical solution measured = 7.5 mL
.
Concentration HCIO4 0.09898 M
Volume titrated 7.05 mL
. Volume blank titration 0.65 mL.
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