) What are the three main parts of a histone deacetylase inhibitor pharmacophore? Explain the function of each part.

Q: What is the maximum number of water molecules that, in theory, one aspartate molecule at pH 7 can…

A: Aspartate molecule comes from the amino acid asparagine, which can bind with water at pH =7,owing to…

Q: anti-egg white injury factor. * vitamin B12 vitamin B2 vitamin B6 vitamin B7

A: Vitamins are the organic substances that are required in smaller quantities for the proper…

Q: anti-egg white injury factor. * O vitamin B12 O vitamin B2 O vitamin B6 O vitamin B7

A: Given statement is :  anti-egg white injury factor ?  Options are :  a. vitamin B12 b. vitamin B2…

Q: Summarize three ways in which an enzyme might lower the energy of a activation of a raction

A: The three ways in which an enzyme might lowe the energy of activation of a reaction are as follows:

Q: glycerol + fatty acids triacylglycerol + H₂O Which types of specificity does this enzyme show?…

A: The stereochemical specificity of an enzyme describes the reaction of the enzyme with one…

Q: Why are irreversible inhibitors considered to be poisons?

A: Solution :       Enzyme inhibitors are those molecules that interact with the enzyme to prevent the…

Q: Aspartate and the enzyme was mixed. After some time, labeled oxaloacetate was added into the…

A: Aspartate Aminotranferase Is a enzyme that catalyzes the reaction a-ketoglutarate to glutamic acid.

Q: 4. How is the racemic mixture of alanine represented?

A: Enantiomers are the stereoisomers that have non-superimposable mirror-image relationship. One of…

Q: ?why is heat an effective means of sterilization إجابتك ?What is the classification of enzymes dila!

A: Sterilization means the destruction of all microorganism including the spores.

Q: How many subunits are present in catalase? What metal ion is necessary for its activity?What two…

A: Catalase is mostly found in all living organisms. Its main function is to protect tissues from the…

Q: Is orange peel esterase and pig liver esterase regioselective if so why

A: The answer of the question is given below with explanation.

Q: What is the difference between tumor suppressors and oncogenes?

A: Difference between tumor suppressor and oncogene

Q: 22. Enzymes that have binding sites for modulators are specifically called O a. zymogens Ob.…

A: Interpretation: Enzymes that have binding sites for modulators are specifically called by which name…

Q: What do COX enzymes synthesise? 3.

A:

Q: The structure of haemoglobin: A. has an alpha-beta architecture. B. is a hetero tetramer. C. is a…

A:

Q: How can we determine whether a reversible inhibitor acts by competitive, uncompetitive, or…

A: Enzymes are the biological catalysts that increase the rate of the reactions occurring inside living…

Q: Cellular chaperones are incredibly important for human health. Which of the following do you think…

A: Cellular chaperones are incredibly important for human health. The factor which is most detrimental…

Q: 1. How will each of the following changes in condition alter the rate of the enzyme-catalyzed…

A: a. Decreasing the temperature from 37°C to 10°C = Temperature is directly proportional to the enzyme…

Q: Is the following an example of competitive or noncompetitive inhibition? Substrate Active site…

A: Enzymes are formed by proteins and they act as catalysts in biological reactions. Enzymes are very…

Q: What TWO strategies could be used for the development of substrate-based inhibitors for HIV aspartyl…

A: Protease is an enzyme in the body that's important for HIV replication. Protease inhibitor drugs…

Q: 26. The storage of zymogens is a means of a. enzymatic feedback inhibition Ob. reversible enzyme…

A: Zymogens, rather than active enzymes, are typically secreted by the human body, because they can be…

Q: Does changing the substrate concentration exhibit the same effect as changing the enzyme…

A: Enzymes are protein molecules which are used to increase the reaction's rate without being…

Q: to cysteine residues in protein active sites. What glycolytic enzyme would be affected? As a result,…

A: A)In the range of metal concentrations analysed we found that only hexokinase and…

Q: Define the following terms: a. carboxybiotin b. cytochrome b5 c. allyl group d. conjugation reaction…

A: Since your question has multiple sub-parts, we will answer the first three sub-parts for you. If you…

Q: In the first step of aminoacyl group linkage to a tRNA, an amino acid reacts with ATP to yield an…

A: The difference between anhydride and mixed anhydride bonds is given in the table below:

Q: The inhibitor competes with the substrate for the active site. Competitive Inhibitor or…

A: To identify: The inhibitor which competes with the substrate for the active site.

Q: Milk contains two classes of proteins curd and whey. Within these two classes all of the following…

A: Proteins are large molecules consisting of different combination of amino acids joined through…

Q: The free energy for folding (delta Gfolding) of a mutant lysozyme at 25oC is – 4.1 kJ mol-1. At…

A: For any change for example A to B. The ratio can be fine by their equilibrium constant. So…

Q: Is the histidine side-chain pKa value higher, lower, or unchanged in an environment surrounded by…

A: Introduction: As per Bronsted-Lowry concept, an acid is a substance that can donate H+ ions and base…

Q: Tove or false : self-phosphorylation of Janus kinase 2 activates it catalytically.

A: True  Self phosphorylation of Janus kinase activates it. It is involved in intracellular signalling.…

Q: Why are superbases important?

A: According to Bronsted-Lowry acid base theory, any compound which is capable of accepting proton is…

Q: Shouldn't it be.... AI2Se3?

A: The compound Aluminium Selenide is made from elements Aluminium and Selenium

Q: Sketch a curve that would describe the expected behavior of phosphofructokinase activity as a…

A: The curve that would describe the expected behavior of phosphofructokinase activity as a function of…

Q: What term is used to describe a species which affects the functioning of an allosteric enzyme?   a.…

A: An allosteric inhibitor by binding to allosteric site changes the protein conformation in active…

Q: The factors that denature enzyme activity are temperature, pH, salinity, alcohol and surface area.…

A: Effect of temperature: Velocity of an enzyme reaction increases with increase in temperature up to a…

Q: Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

A: A number of clinical studies have shown that consumption of complex carbohydrates is inversely…

Q: Enzymes that are allosterically regulated Select one: a. Are multimeric proteins b. Do not behave…

A: Enzymes are biological catalysts that function to speed up the rate of reaction by reducing the…

Q: What is an allosteric inhibito

A: Given : Allosteric inhibitor.  To find : general details about allosteric inhibitor.  Solution :…

Q: 10. Enzymes that have binding sites for modulators are specifically called a. zymogens Ob.…

A:

Q: Avidin is commonly found in uncooked egg white. Consuming excessive amount of uncooked egg whites is…

A: Egg whites contain high levels of avidin, a protein that binds biotin strongly. When cooked, avidin…

Q: Pyruvate kinase variant PKM2 favors tumorigenesis because it can be turned off as a response to…

A: The addition of a product (inhibitor) causes a drop in reaction rate due to its effect on the…

Q: 23. Which of the following is NOT a blood group antigenic determinants? L-fucose D-fucose…

A: Which is not a blood group antigens determinants given below.

Q: Provide the protein/s found in the following:   Egg   Milk

A: 1. Egg- Egg consists of many proteins. But ovalbumin is the major protein found in egg nearly 54 %.…

Q: What is the substrate of alpha- amylase? What is the optimum temperature for alpha amylase? Will the…

A: Optimum temperature: At which the temperature, rate of the reaction is high, that temperature is…

Q: What would happen to pH and protease activity if the fruit juice were diluted by deionized water?

A:

Q: Q29: Inosinate is a pyrimidine that can ultimately be converted to cytidylate and thymidylate. O a…

A: Purines and pyrimidines are nitrogenous bases. Purines include adenine and guanine, while the…

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.