What does whole exome sequencing reveal?

Q: What is linker scanning mutagenesis?

A: Answer: Introduction: Old-style approaches, containing linker-scanning mutagenesis includes…

Q: What is metagenome sequencing?

A: Metagenomics is the study of microbial communities in their environment by using modern genomic…

Q: Why is genome database and annotation relevant to Genome sequencing?   Are there any examples?

A: Genome: the set of genes. Genome database: it is the collection of all information on the human…

Q: What is positional cloning?

A: Gene cloning is the process in which any gene of interest is amplified, that is, several copies of…

Q: Which is a limitation of using massively parallel sequencing ?

A: It is a term used to describe the method of high-throughput DNA sequencing to determine the entire…

Q: How big is the exome?

A: Exomes are the part of the genome, which consists of exons that remain within the mature…

Q: Differentiate between Sanger sequencing and next generation sequencing?

A: The process of determining the nucleic acid sequence is known as DNA sequencing.

Q: What is the principle of next generation sequencing?

A: The process of determining the nucleic acid sequence is known as DNA sequencing.

Q: How does gene cloning produce many copies of a gene?

A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…

Q: How does a DNA microarray work?

A: Gene microarray technology enables to deposit many different DNA sequences on a small glass slide,…

Q: What is geneticengineering?

A: Genetic engineering, also known as genetic modification. Use of genetic engineering in agriculture…

Q: What is the Pros and Cons of Cloning?

A: Answer  Cloning is the brst way to increase the product in more number bearing the same generic…

Q: What is hierarchical sequencing?

A: Basically there are two approaches for the sequencing of large complex genome. They are hierarchical…

Q: How are genes recognized within genome sequences?

A: Meaning of Genes: Genes refers to a specific sequence of nucleotides in DNA or RNA that is located…

Q: What are gene microarrays? How are microarrays used?

A: The process of forming a single double-stranded nucleic acid molecule by combining two…

Q: What provides a convenient bridge between the low resolution of a karyotype and the ultra-high…

A: Introduction  Cytology refers to the study of cell such as cell morphology, physiology etc. As we…

Q: What is involved in DNA sequencing?

A: DNA stands for deoxyribonucleic acid. It is the genetic material of the organisms that transfer from…

Q: How is exome sequencing helps in identifying mutations?

A: Exome sequencing refers to the genomic technique in which the sequencing of all the protein-coding…

Q: What does whole exome sequencing test for?

A: Exomes are part of the genome, which contains only the coding portions of the genes that is the…

Q: What is the point of genome sequencing?

A: DNA is the main constituent of the chromosome. It contains all information about protein that forms…

Q: How to use a microarray for transcriptome analysis ?

A: Transcriptome is the complete set of the mRNA molecules expressed in an individual . It is termed as…

Q: What does massively parallel sequencing mean?

A:

Q: What is a read (Sanger sequencing)?

A: DNA sequencing is the process of determining the sequence of nucleotides (adenine, guanine,…

Q: How are different variable region sequences generated?

A: Ans: The variable regions of the antibody have two chains heavy and light chains. They form a part…

Q: HOw many times can DNA segments be transcribe? Also, can mRNA molecules be reused?

A: Transcription is the process in which mRNA is synthesized from DNA. This process takes place in the…

Q: What is the motive behind Genome Project 10K?

A: The advent of low-cost, high throughput sequencing has ushered in a new age of genome science and…

Q: What is the difference between whole exome and whole genome sequencing?

A:

Q: What does whole genome sequencing reveal?

A:

Q: What is shotgun cloning or shotgun sequencing ?

A: Cloning is the process of creating an identical copy of something. In biology, it refers to the…

Q: How does positional cloning work?

A: Positional cloning is a technique used in laboratories for locating the position of…

Q: How many male/female sheep are needed to clone one? Cancloning be done by using adult cells?

A: One male and one female sheep is required to clone one because we need one male gamete and one…

Q: What is the principle of Sanger sequencing?

A: DNA sequencing is the process of determining the sequence of nucleotides (adenine, guanine,…

Q: What are the main  differences between whole genome sequencing and whole exome sequencing?

A: whole genome sequencing is sequencing the entire genome of the organism, where as whole exome…

Q: How new sequencing methodologies are replacing traditional genomic DNA libraries ?

A: The term genomic DNA library is associated with DNA fragments collection comprising an organism's…

Q: What is DNA microarray used for?

A: It is a laboratory tool used to detect the expression of thousands of genes at the same time. The…

Q: How much of the human genome is coding?

A: The genes are the components of the genome that direct specific functions in the cell. Their…

Q: What are frame-shift insertion?

A: Mutations are changes that occurs in the deoxyribonucleic acid (DNA) sequence, either due to…

Q: What is the Pan genome  ?

A:

Q: How does positional cloning work and What is the basic principle of positional cloning?

A: Positional cloning is a technique used in laboratories for locating the position of…

Q: What is meant by sequencing by synthesis?

A: Genome sequencing is the technique that involves the generation of genetic information found in DNA…

Q: How accurate is whole exome sequencing?

A: The goal of exome sequencing, also known as whole genome sequencing is to identify genetic variants,…

Q: what are Several Limitations of positional cloning?

A: Positional cloning is one of the laboratory technique of gene identification. In this method, gene…

Q: What is the primary disadvantage of Sanger sequencing?

A: Sanger sequencing the target DNA sequence is determined by copying it into the fragments of…

Q: What is a n automated DNA sequencing?

A: Deoxy ribonucleic acid (DNA) is the genetic material of most organisms that carry coded genetic…

Q: What is known as minisatellites ?

A: In biology, the genotype can be outlined as the genes collection of an individual. The expression of…

Q: What are Short hybridization probes?

A: A probe is a stretch of single stranded ribonucleotides (RNA) or deoxyribonucleotides (DNA). DNA…

Q: What is cloning vector?

A: Deoxyribonucleic acid (DNA) is a molecule made up of two polynucleotide chains, DNA carries all of…

Q: What can exome sequencing do for you?

A: The sequencing of the nucleic acid is the process through which the exact sequence of the nucleotide…

Q: What is single molecule sequencing in real time (SMRT) ?

A: DNA sequencing is a technique for determining the order of the four nucleotide bases found in DNA:…

Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.