What is the best way to accomplish the following transformation? HO CH2NH2 O 1. NaCN, HCI, 2. H3O*, heat O CH3NH2, trace H* O 1. NaCN, HCI, 2. H3O* O 1. NaCN, HCI, 2. H2, Raney Ni O 1. NaCN, HCI, 2. NaBH3CN, 3. H30*

What is the best way to accomplish the following transformation? HO CH2NH2 O 1. NaCN, HCI, 2. H3O, heat O CH3NH2, trace H O 1. NaCN, HCI, 2. H3O* O 1. NaCN, HCI, 2. H2, Raney Ni O 1. NaCN, HCI, 2. NaBH3CN, 3. H30*

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter8: Haloalkanes, Halogenation, And Radical Reactions

Section: Chapter Questions

Problem 8.28P

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Question

What is the best way to accomplish the following transformation?
HO CH2NH2
?
O 1. NaCN, HCI, 2. H3O*, heat
O CH3NH2, trace H*
O 1. NaCN, HCI, 2. H3O*
O 1. NaCN, HCI, 2. H2, Raney Ni
O 1. NaCN, HCI, 2. NABH3CN, 3. H30*

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The transformation can be achieved via the following way

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