What is the structural difference between normal EGFR and oncogenic receptor, e.g. ERbB? How does it affect its activity?

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Q: What is the importance of understanding the interactions between the receptor binding domain of the…

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Q: What are the molecular basis of signal transduction of: A. Homodimer Steroid Receptor B. Heterodimer…

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Q: Which of these proteins contain IDRS, and how do the IDRS impact signaling?

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Q: Through recombinant DNA methods, a modified steroid hormone receptor was prepared that consists of…

A: The ligand-binding domain can be defined as the type of domain that allows the binding of the…

Q: What method might be used to determine the extent of binding of hemin to the 3 NEAT domains of Hbp2?

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Q: Why do signals indicating damage to cells result in increase in the expression of p21Cip1?

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Q: Which of the following statements is FALSE?  The mammalian glucocorticoid receptor: awaits the…

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Q: What are adverse effects associated with the use of Tocilizumab and dexamethasone in COVID-19.

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Q: Which G-protein-coupled family subtype is Prolactin? Prolactin (PRL) receptors are G-protein-coupled…

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Q: What is "tocilizumab"? Specify its nomenclature and explain its role in the treatment of COVID-19.

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Q: Which of the following results in transcriptional attenuation?

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Q: Can anyone suggest a way of increasing phosphorylation of IKK alpha (Ser176/180)? Any potent…

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Q: One of the key components in vertebrate limb development is the polarizing region, also known as the…

A: In the limb bud, an ectoderm layer surrounds the undifferentiated mesenchyme. Bones, tendons,…

Q: What is the purpose of having a sex hormone binding protein within the blood stream? What is the…

A: Hi! Thank you for your question. But as you have posted multiple questions and have not mentioned…

Q: Are any of the following feasibly linked to COVID-19 susceptibility? . Leucine zipper transcription…

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Q: The use of an SH2 domain binding inhibitor would be predicted to: O Decrease binding of SOS with RAS…

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Q: Explain the relationship between the variable number of tandem repeats in the insulin promoter…

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Q: How would you produce a mouse that is homozygous fora rat growth-hormone transgene?

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Q: GC (Glycocorticoids) binds to the glucocorticoid receptor (GR), which leads to the transcription of…

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Q: Comment on the difference in expression patterns between APETALA1 and CYCLIN1. How do the…

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Q: What evidence suggests that cognition in mice is influenced by epigenetic changes?

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Q: In early mammalian development, compaction would likely be blocked by inhibiting expression of which…

A: ANSWER;- d) Cdx2

Q: The egfr kinase independent transactivation of the ras pathway does require egfr. Explain this…

A: EGFR is a cell surface receptor that binds to certain growth factors and sends signals to the cell's…

Q: Describe the steps that need to occur for the glucocorticoid receptor to bind to a GRE.

A: Glucocorticoids can be defined as the are hormones that are essential for life and their synthesis…

Q: Draw a cell signaling pathway following EGFR activation in host cells with the possible downstream…

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Q: Discuss the family of nuclear hormone receptors and explain how ligand binding to such a receptor…

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Q: Why is zinc being used as prophylaxis for COVID-19?

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Q: What are the consequences of inhibiting the m-phase promoting complex

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Q: Discuss genetic evidence that lacI encodes an allostericrepressor protein that binds the operator…

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Q: Below is a list of mutations commonly found in different components of the hormone-signaling…

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Q: What is the main lincRNA involved in X-inactivation, and what is known about its function?

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Q: Muckle–Wells syndrome is an autosomal dominantly inherited disease due to mutations in NLRP3.…

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Q: either loss of responsiveness to a given hormone or production of a continuous signal even in the…

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Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.