Below is a list of mutations commonly found in different components of the hormone-signaling pathways. | Mutant #1: The icRH undergoes a loss-of- function mutation. | Mutant #2: GSK-3B can no longer be phosphorylated. I Mutant #3: ERK is constitutively active. | Mutant #4: Lyn undergoes a gain-of function mutation. | Mutant #5: The cyclin A gene's DNA is highly compacted and inaccessible. la. Mutations in the signalling pathways depicted above have been associated with an increased incidence of several types of cancer. Which of the above mutations (#1-5) could potentially cause cancer in an individual? Be sure to explain why.

Below is a list of mutations commonly found in different components of the hormone-signaling pathways. | Mutant #1: The icRH undergoes a loss-of- function mutation. | Mutant #2: GSK-3B can no longer be phosphorylated. I Mutant #3: ERK is constitutively active. | Mutant #4: Lyn undergoes a gain-of function mutation. | Mutant #5: The cyclin A gene's DNA is highly compacted and inaccessible. la. Mutations in the signalling pathways depicted above have been associated with an increased incidence of several types of cancer. Which of the above mutations (#1-5) could potentially cause cancer in an individual? Be sure to explain why.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 5TAHL

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