What type of substances are angiostatin and endostatin and where are they produced? What do they do?

Comprehensive Medical Assisting: Administrative and Clinical Competencies (MindTap Course List)
6th Edition
ISBN:9781305964792
Author:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy Correa
Publisher:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy Correa
Chapter17: Medical Coding
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please help me I can't find answers for these questions: here is the link for the article 

https://www.pbs.org/wgbh/nova/transcripts/2805cancer.html

  1. What type of substances are angiostatin and endostatin and where are they produced? What do they do?

A) describe the experiments using cow bones to discover anti-angiogenic substances. Why was this used as a source of these potential proteins?

B) describe the “accidental” discovery of a novel antiangiogenic substance because of lab contamination? 

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