This asymptomatic disorder, typically discovered accidentally, is caused by mutations in the SLC36A2 or SLC6A20 genes.

Q: When human hemoglobin undergoes a mutation, the mutant protein usually does not replace all of the…

A: The cytosol of red blood cells contains the oxygen-carrying globular protein hemoglobin, which is…

Q: What is the APC payment for HCPCS code 71046? Explain.

A: APC weight =1.56 Conversion factor CF $80.79 Wage Index 0.9445

Q: What are the reasons why most of the clinical features of the diseases in krebs cycle involve muscle…

A: The Krebs cycle occurs in the mitochondria. It occurs in every cell where oxygen is used to produce…

Q: A 25-year old man is concerned about his fmaily history of ankylosing spondylitis. He has not yet…

A: Ankylosing spondylitis is a condition where prolonged inflammation can lead to the fusion of bones…

Q: Even single point mutations can have a significant effect on protein function. Describe how point…

A: A point mutation is a mutation that only affects a single nucleotide of nucleic acid. Point…

Q: Below is a primary sequence alignment between the wild-type hemoglobin protein, and the hemoglobin…

A: Hemoglobin can be described as a pigmented protein that forms a component of the red blood cells or…

Q: Explain why the gene for sickle cell anemia may be beneficial to humans at some point. Describe…

A: Sickle cell anemia is an autosomal disease in which the red blood cells become sickle-shaped. In…

Q: True or False: An individual with sickle-cell anemia is caused by a missense mutation.

A: Missense mutation is a type of genetic alteration in which a single base pair substitution alter…

Q: Baby Jordan was born in the middle of the COVID-19 crisis in Chicago, Illinois. His parents Dane and…

A: Since we only answer up to 3 sub-parts, we'll the first 3. Please re-submit the question and specify…

Q: The SARS-CoV-2 genome is a polycistronic genome. What does the term polycistronic refer to

A: The covid pandemic as we all know is the disease associated with virus SARS-CoV-2.

Q: I read that vinyl chloride exposure is associated with an increased risk of a rare form of liver…

A: Cancer is the condition of uncontrolled cell division.

Q: Ultraviolet light causes thymine dimers to form in DNA. Some individuals are genetically incapable…

A: Genetic variation is very important for evolution, but genetic stability is crucial for survival…

Q: Approximately 1 in 100 West Africans suffer from sickle-cell anemia. Given the often devastating…

A: A genetic disorder is a disease, which is caused by abnormalities in a person’s Deoxyribonucleic…

Q: What are some possible social and ethical issues associated with mitochondrial replacement therapy…

A: Mitochondrial replacement therapy (MRT) is the replacement of mitochondria in one or more cells to…

Q: Explain Synpolydactyly caused by mutations in the human HoxD13 gene.

A: Synpolydactyly (SPD) is a rare congenital distal limb malformation, which is characterized by the…

Q: What is the pathogenesis of Isolated IgA Deficiency?   Please provide flow chart

A: Immunology is a section of biology that includes the study of molecules, cells, and organs that…

Q: What would happen if the retinoblastoma protein wasn't able to bind to the E2F transcription factor?

A: The retinoblastoma protein (pRb) is a tumor suppressor protein that helps to prevent excessive cell…

Q: PBR327 is descended from PBR322. Explain TWO (2) advantages of using PBR327.

A: pBR327 vectors are created by deleting nucleotides between 1427 and 2516 from pBR322. Those…

Q: Which ONE of the following molecular abnormalities is associated with the POOREST prognosis in acute…

A: Acute myeloid leukemia is a disease that interferes in the production of normal blood cells. It is a…

Q: Which of the following disorders arises from translocation events?   Huntington’s disease   Burkitt…

A: Translocation is caused due to separation of a chromosome segment and its union toa nonhomologous…

Q: Explain why mutations of the Arg residue in Gsα that is ADPribosylated by cholera toxin are…

A: A potential virulence factor developed by Vibrio cholerae, which is the causative factor of cholera…

Q: here is a benign congenital condition called Hereditary Persistence of Fetal Hemoglobin (HPFH) in…

A: Hereditary Persistence of Fetal Hemoglobin is the condition when there is still fetal hemoglobin…

Q: Question 21:  Write the characteristics clinical features of Von Gierke's disease.

A: Von Gierke's disease is a glycogen storage disorder whic occur due to deficiency of enzyme…

Q: What is the total APC payment for HCPCS codes 66984, 71020, and 78740? Round the answer to two…

A: Given,  APC weight 24.56 Conversion factor CF $80.79 Wage Index 0.9445 AS PER the OPPS formula :…

Q: which gene is mutated in type la maple syrup urine disease?

A: Maple syrup urine disease is associated with problems with feeding, vomiting, low energy levels in…

Q: Sickle cell anemia is caused by—     a mutation in a cell surface receptor.     malfunction of…

A: Sickle cell Disease or SCD is one of the blood diseases that are usually inherited. The most…

Q: What type of mutation is sickle cell anemia? Explain the molecular basis of sickle cell anemia.

A: Sickle cell anemia is an abnormal condition that arises due to the mutation in the beta-globin chain…

Q: For the following diseases, describe the best technique for diagnosing them.  Please make sure you…

A: Factor V Leiden is a mutated form of blood clotting factor V. Blood clotting factors are proteins…

Q: Describe two mutations that are associated with the development of leukaemia and how these two…

A: The type of cancer that will begin in the blood-forming tissue, generally in the bone marrow, is…

Q: Is there non-functional leukopoiesis in Leukemoid Reaction

A: Answer: Leucocytes or leukocytes are the cells found in blood which are responsible for protecting…

Q: KEYWORDS Define the following keywords: gene. hemoglobin. mutation, sickle-cell anemia

A: The red color is imparted to RBC by oxygen-carrying hemoglobin present in the blood. The transport…

Q: Please explain the role of Ubiquitin Ligase Activity in the regulation of apoptotic cell death.

A: Numerous enzymes in the ubiquitin system govern both autophagy and cell death, and all these cell…

Q: The mutation causing sickle-cell anemia in humans, which changes the normal T to an A in the sixth…

A: Hemoglobin is a normal globin protein with heme (iron) in the red blood cells. It helps to…

Q: Sickle-cell anemia is a genetic disorder of individuals homozygous for a mutation of hemoglobin that…

A: Sickle cell anemia is an autosomal disease in which the red blood cells become sickle-shaped. In…

Q: Baby Jordan was born in the middle of the COVID-19 crisis in Chicago, Illinois. His parents Dane and…

A: 1. Tyrosine and melanin  are the two amino acids  that are involved An enzyme ( tyrosinase )helps…

Q: Patients with severe cases of COVID-19 (the disease caused by the coronavirus) may not be able to…

A: The corona virus infects the person and causes  COVID-19 disease in them. The  COVID-19 disease…

Q: Why are proteins synthesised from spirulina called single cell anemia?

A: Single-cell proteins are the proteins that are edible and are derived from single-celled organisms.…

Q: How does the loss of the Adenomatous polyposis coli (APC) protein lead to the deregulation of…

A: Answer: Introduction: Familial adenomatous polyposis (FAP) is an inherited syndrome categorized by…

Q: Muckle–Wells syndrome is an autosomal dominantly inherited disease due to mutations in NLRP3.…

A: Muckle-wells syndrome is the disorder characterized by periodic episodes of fever, skin rash and…

Q: Cystinuria is caused by mutations in the cystine transporter, which is an antiporter which…

A: A mutation is a permanent change in the DNA of a cell such that the sequence deviates from what is…

Q: The N1303K mutation in the CFTR gene of CF patients is autosomal dominant disorder due to insertion…

A: The N1393K mutating in CFTR gene of CF is autosomal recessive disorder where asparagine to lysine…

Q: Retroviral delivery of the gene coding for Combined Immunodeficiency. treats individuals with Severe…

A: Successful gene therapy that is performed with the retroviral vectors neceserily requires robust…

Q: Which of the following drugs inhibits protein synthesis through binding to ribosomal 30S subunit: a.…

A: Aminoglycide class of drugs works by irreversibly binding to the site on the bacterial 30S ribosome,…

Q: What is the APC payment for HCPCS code 66984? Explain.

A: APC weight 24.56 Conversion factor CF $80.79 Wage Index 0.9445