When hydroxide is used as the base to carry out an E2 reaction on a vinylic halide, the reaction usually needs to be heated significantly. As shown below, such a reaction involving the E isomer typically requires much higher temperatures. Why is this so? Z isomer E isomer Br КОН КОН 70 °C 200-230 °C Br Br 70% 67%

Q: ?nucleophiles اختر واحدة أو أكثر a. CH4 Ob. Br c. H20 d. NH3 e. H2C=CH2 (-)f. OH (+)g. Br h. BH3

A: The electron rich species are termed as nucleophiles. Nucleophiles can be neutral or negatively…

Q: Choose all the nucleophiles OH-     H3O+     NH4+     CH3OH     (CH3)3CLi     CH3CH2CH3     NaNH2…

A: Nucleophile :-A chemical species which have free pair of electronsor can denote pair of electrons…

Q: A hydrogen and the leaving group have to be antiperiplanar in which reaction? O E2 O inversion O SN1…

A: The leaving groups and hydrogen leave when from the given organic substrate if the reaction goes…

Q: 1. In following pairs of nucleophilic substitution reaction, which one have higher reaction rate?…

A: Note: According to our guidelines we are supposed to answer only first three subpart.  Kindly repost…

Q: camparing vanious alkyl halides reactivity toward SN1 reactions using water as a nucleopnile Entry #…

A: Here we have to explain the better leaving group from the given experimental data of SN1 reaction in…

Q: Draw the major organic product of the reaction shown below.

A:

Q: We mentioned in the chapter opener (p. 1198) that tetrodotoxin has been synthesized using a…

A: The given reaction is,

Q: A hydrogen and the leaving group have to be antiperiplanar in which reaction? O SN1 O inversion O…

A:

Q: Circle the least reactive compound from the following in an SN1 reaction: Br Br Br С. В. Br D. O B

A: SN1 reaction is a substitution reaction.

Q: In Friedel-Crafts alkylation, which compound below cannot be an electrophile? Br Br Br Br D A B

A: An electrophile is a chemical species produced by the removal of the leaving group with its bonding…

Q: Consider the substitution reaction shown below. By what mechanism will the reaction proceed? Br…

A: There occur substitution reaction.

Q: In each of the following reactions, the aromatic ring has just one chemically distinct, aromatic H,…

A: The given reactions are represented as follows:

Q: Which of the following ring cyclization reactions would occur at the fastest rate? A /a В в C C D D…

A: Neighbouring group participation (NGP) (also known as anchimeric assistance) in organic chemistry…

Q: A student attempted to synthesize an epoxide according to the reaction scheme shown here, but no…

A:

Q: 8. a) Propose a mechanism for the following electrophilic aromatic substitution reaction used to…

A: Given

Q: A= C10H16Br2 Brz, CCI, PHCOOH Brz, H,O D= C10H160 E= C10H16 B= C10H17OBr 1. Og 2. Zn, ácido acético…

A: Ozonolysis is defined as the reaction of alkenes or alkynes with ozone gas in which the cleavage of…

Q: Which is the most stable resonance structure for the arenium ion that leads to the major product of…

A: Answer:- This question is answered by using the simple concept of directive effect of ketone on…

Q: SN1 reactions undergo carbocation rearrangments, but E1 reactions do not because the carbocation…

A: The given statement has to be given as true or false,

Q: Br A Br B Br C D -Br

A: SN1 reaction The SN1 reaction is a nucleophilic substitution reaction where the rate-determining…

Q: How Reactivity Depends on the Basicity of the Leaving Group?

A: Applying basic concepts of relationship between  leaving ability and base character of leaving…

Q: The nucleophile approaches from the opposite side of the carbon with the leaving group in which…

A: It is SN2 reaction. In SN2 reaction i.e nucleophilic substitution biomolecular,   one bond is broken…

Q: In the SN1 reaction, the 2nd step is the rate determining step. The SN1 reaction yields a total…

A: Given  In SN1 Reaction, the second step is the rate-determining step. The SN1 reaction yields a…

Q: Which of the following can undergo E2 Elimination? Br. Br. Br Br В B&D A & C

A: Elimination reaction takes place when two atoms are removed from one molecule . At first H atom…

Q: Rank the following alkyl halides in order of increasing reactivity in E2 elimination. Then do the…

A: Generally the increasing order of the alkyl halide in E1 and E2 elimination reaction will be methyl…

Q: 1. For the following reactions, predict the major product. lio peroxides). peroxides H2504 C) A H20

A:

Q: A nucleophilic substitution reaction is shown below. Identify the nucleophile. I A) CH:S- B) Na II…

A: Nucleophile:  In a chemical reaction a nucleophile is a species that forms bonds with electrophiles…

Q: Which of the following reactions often competes with the SN2 reaction needed to make an ylide from…

A: The correct option is (b) i.e. E2 mechanism.

Q: (i) Write both reactions using bond-line presentation and, using arrows providing a mechanistic…

A: Sn2 reaction is bimolecular substitution reaction.

Q: Rank the substrates below in order of increasing reactivity (from slowest to fastest) in a…

A: Considering SN2 mechanism and leaving ability of leaving group.

Q: How does gold help to catalyze the reaction in the gold catalysis experiment? о а. It deprotonates…

A:

Q: Br2 / N2OH R-CO-NH2 R-NH2 H2O

A: It is an example of Hofmann elimination reaction. Here primary amine formed as the product.

Q: Halogenation readily takes place at an α carbon of a ketone or aldehyde under basic conditions if…

A: In an acid base reaction, a base abstracts the most acidic proton. The acidic proton is the one…

Q: Which halides are unreactive in a Friedel–Crafts alkylation reaction?

A: The Friedel–Crafts reactions are a set of reactions developed  to attach substituents to an aromatic…

Q: In the last step in the mechanism of the nitration of benzene, a base will take a proton to restore…

A: The nitration of benzene is carried out in the presence of concentrated nitric acid and concentrated…

Q: Rank A, B, and C in order of increasing SN1 reactivity.

A:

Q: In the formation of the following ether, which reaction is preferred and why? NOC NEOCH, CH,OH O…

A: The reactions given are,

Q: Which one of these provides the strongest nucleophile in an SN2 reaction? a) HC=N b) NaC=N c) NH3 d)…

A: The nucleophilicity of the above mentioned compounds depends on the extent of the dissociation of…

Q: Draw the major organic product of the reaction shown below. HO, NaNH2 +

A:

Q: Which of the following substrates will have the fastest rate of reaction with NaCN in DMSO? O A) B)…

A: Given: Alkyl halide + NaCN in polar aprotic solvent DMSO

Q: Which undergoes SN1 reaction fastest? BAU2000 54 Br Br Br Br

A:

Q: Which site in the molecule below is most reactive in electrophilic aromatic substitution? (а) OH (b)…

A: Answer:- This question is answered by using the simple concept of directive effect of disubstituted…

Q: Rank the following substrates in order from slowest SN2 reaction rate to fastest. Br Br Br H3C Br A…

A: SN2 stands for nucleophilic substitution reaction of order 2. In this reaction, the rate of the…

Q: During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important.…

A: The correct answer about Fridel crafts reaction is given below

Q: Based upon the following energy diagram, is this reaction an E1 or an E2 elimination? reaction…

A: E1 elimination reaction is proceeds via formation of intermediate, while E2 elimination reaction…

Q: Rank these substrates in order of increasing ability to undergo a nucleophilic substitution aromatic…

A:

Q: Br, Br HBr (xs)

A: SN1 type mechanism  follow.