When one of the acetyl CoA is processed through the citric acid cycle, how many times does a secondary alcohol group is oxidized to a ketone group?
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When one of the acetyl CoA is processed through the citric acid cycle, how many times does a secondary alcohol group is oxidized to a
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- Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.
- How many acetyl CoA molecules can be produced during the complete β-oxidation of this fatty acid?Two carbon atoms are fed into the citric acid cycle as acetyl-CoA. In what form are two carbon atoms removed from the cycle?If a fatty acid containing 13 carbons is subjected to Beta oxidation, how many molecules of Acetyl CoA can be produced?
- Why is acetyl CoA an especially appropriate activator for pyruvate carboxylase?Which reaction in the citric acid cycle is most analogous to the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate? What kind of enzymebound intermediate is formed in both reactions?The same reactions that were seen in the process of converting pyruvate to acetyl-S-CoA, occur in step ____ of the citric acid cycle as ____________ is converted to _________________.