What is alpha keto glutarate dehydrogenase complex?. explain very briefly.

Q: Why does it make good metabolic sense for phosphoenolpyruvate carbox- ykinase, rather than pyruvate…

A: Phosphoenolpyruvate carboxylase is an enzyme in the family of carboxy-lyases found in plants and…

Q: What structurtal property of mono- and polyunsaturated fatty acids prevents oxidation of these…

A: Fatty acids are important lipid molecules. They are characterized by the presence of a carboxylic…

Q: Why Alpha-Ketoglutarate dehydrogenase (a-KGDH) called deficiency? What are the probable causes?…

A: Alpha-ketoglutarate dehydrogenase (alpha-KGDH) is a tightly controlled enzyme that regulates…

Q: What is the function of the kinase associated with the pyruvate dehydrogenase complex?

A: Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into…

Q: What are some types of enzyme-catalyzed reactions that require pyridoxal phosphate as a coenzyme?

A: Pyridoxal phosphate serves as a coenzyme for several enzyme-catalyzed reactions. It is an active…

Q: The clinical symptoms of two forms of galactosemia—deficiency of galactokinase or of UDPglucose:…

A: Galactosemia is a rare gentic metabolic disorder that affects an individual's ability to metabolize…

Q: Hypercholesterolemic individuals taking statins are sometimes advised to take supplements of…

A: The high cholesterol level in the blood of the body is referred to as hypercholesterolemia. It is an…

Q: What are the nonoxidative reactions of the pentose phosphate pathway, and why are they important?

A: Pentose phosphate pathway is an alternative to glycolyis and TCA cycle for oxidation of glucose.…

Q: Which of the following does not correctly describe the isozymes of lactate dehydrogenase (LDH) in…

A: Lactate dehydrogenase (LDH) is an enzyme which catalyzes the conversion of lactate to pyruvate along…

Q: Mercuric ion and methanol are inhibitors of alcohol dehydrogenase. Explain.

A: Alcohol (ADH) dehydrogenase is an enzyme that helps in the interconversion of alcohol into ketones…

Q: Explain the biochemical consequences of Glucose-6-Phosphatase deficiency that results in gout due to…

A: The enzyme glucose-6-phosphatase regulates the release of glucose from glycogen stored in the liver.…

Q: What is the difference between glutamine synthetase andglutaminase?

A: Enzymes are proteins that have catalytic powers.

Q: Under anaerobic circumstances, why is pyruvate converted to lactate?

A: Anaerobic Glycolysis is the process of glucose oxidation that occurs when oxygen levels are low,…

Q: Carboxylation of acetyl CoA to produce malonyl CoA is catalyzed by a. Malonyl COA carboxylase

A: Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…

Q: Explain why the amino acid tryptophan is both ketogenicand glucogenic.

A: The amino acid is the organic acid that contains alpha carboxyl group, alpha amino group, hydrogen…

Q: Are any of the intermediates in the β-oxidation pathway chiral? Explain.

A: Chiral: it is defined as a molecule with lack of internal plane of symmetry and has four different…

Q: Predict which one of the five steps of the α-ketoglutarate dehydrogenase complex reaction is…

A: Alpha-ketoglutarate dehydrogenase is a highly regulated enzyme, which could determine the metabolic…

Q: Why is oxaloacetate an intermediate in gluconeogenesis?

A: Glucose is the primary source of energy in the body. Glucose is broken down into pyruvate by…

Q: How many moles of ATP are synthesized by adding stearate to TCA through B-oxidation? Why is that?…

A: From the Beta oxidation process: The P/O ratios, which give the number of ATP produced per molecule,…

Q: Why is pyruvate referred to as the hub of glucose oxidation?

A: Glycolysis is the oxidation of glucose to produce carbon dioxide and water. Pyruvate is the…

Q: What is the physiological significance of the isozymic forms of lactate dehydrogenase (LDH)? Explain…

A: Lactate dehydrogenase (LDH) is a tetrameric protein that catalyzes the reversible conversion of…

Q: Outline the mechanism of the conversion of a-ketoglutarate to succinylCoA catalyzed by…

A: The last common mechanism for the aerobic oxidation of fuel molecules is the citric acid cycle. In…

Q: What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase…

A: Introduction Respiration is a metabolic process involving the oxidation of organic compounds to form…

Q: In what way is the observed mode of action of hexokinase consistent with the induced-fit theory of…

A: In enzymology, allosteric regulation is the inhibition or activation of an enzyme by a small…

Q: Why is citrate an appropriate inhibitor of phosphofructokinase?

A: Citrate allosterically inhibits  phosphofructokinase by enhancing the inhibitory effect of ATP

Q: Why is the TCA cycle is important for both anabolic and catabolic reactions?

A: After each turn of the TCA cycle, oxaloacetate is regenerated and can combine with another…

Q: Which of the following glycosidic linkages is hydrolyzed by the a-amylase?

A: α amylase enzyme belongs to the enzyme group of amylase. Amylases hydrolyses the α-1,4-glycosidic…

Q: Why is gluconeogenesis labeled as enzymatic by-pass reactions?

A: Glucose is a central carbohydrate in body. It is the instant energy generating molecule. Whenever…

Q: What is the role of glutathione in protection against damage by reactive peroxides? Why is the…

A: Ans: Glutathione: It is the antioxidant molecule that consists of glutamine, glycine as well as…

Q: N -Acetylglutamate is required as a cofactor in the synthesis of carbamoyl phosphate. How is…

A: N-acetyl (NAG) glutamate is considered as a cofactor, in the synthesis of the carbamoyl phosphate,…

Q: Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate…

A: Guconeogenesis is the process whereby glucose is formed from non-carbohydrate metabolic substrate…

Q: What steps of the citric acid cycle are regulated? How and why are they regulated?

A: In metabolic pathways, the regulation of key enzymes is essentials for the productions of…

Q: Explain why people with a hereditary deficiency of carnitine acyltransferase II have muscle…

A: Carnitine acyltransferase II is a mitochondrial membrane protein which is transported mitochondrial…

Q: what are the components of Pyruvate dehydrogenase Enzyme complex ?

A: Pyruvate dehydrogenase Enzyme  complex is made up of three Enzymes and requires 5 coenzymes .

Q: How much energy is attained with the complete oxidation of the ketone body D-3-hydroxybutyrate?

A: Ketogenesis is the biochemical catabolic process where it processes ketone bodies such as…

Q: Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate…

A: Guconeogenesis is the process whereby glucose is formed from non-carbohydrate metabolic substrate…

Q: In the B-oxidation of a saturated, even chain fatty acid, four basic steps are involved. Describe…

A: In mitochondria,  acetyl CoA is important component for Krebs cycle . There are various sources of…

Q: What is meant by the term beta-oxidation?

A: Biochemistry is a branch of science that deals with the study of chemical processes related to the…

Q: What is the effect of the cholesterol diet on the amount of HMGCoA reductase protein?

A: Cholesterol is a compound which consist of cyclic ring and it is essential component which is…

Q: B-"3-Hydroxy-3-methylglutaryl CoA" is a common metabolite in two pathways, mention the names of…

A: When two molecules of acetyl CoA condenses to form acetoacetyl CoA and this acetoacetyl CoA…

Q: When the identical subunits of chicken liver fatty acid synthase are dissociated in vitro, all of…

A: The fatty acid synthase is a multi-enzyme protein. It catalyzes the synthesis of fatty acids. In…