Why is acetyl CoA an especially appropriate activator for pyruvate carboxylase?
Q: Why does it make good metabolic sense for phosphoenolpyruvate carbox- ykinase, rather than pyruvate…
A: Phosphoenolpyruvate carboxylase is an enzyme in the family of carboxy-lyases found in plants and…
Q: What is alpha keto glutarate dehydrogenase complex?. explain very briefly.
A: Tri carboxylic acid (TCA) cycle is an amphibolic pathway that means it involves both catabolic and…
Q: What is the function of the kinase associated with the pyruvate dehydrogenase complex?
A: Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into…
Q: What are the 4 steps that must happen to convert pyruvate into acetyl coA? What 3 enzymes are…
A: Pyruvate oxidation is the odd one out of the four stages of cellular respiration; it is…
Q: Outline the steps involved in the production of malonylCoA from acetyl-CoA.
A: Fatty acids are the long hydrocarbon chain compound attached to the carboxylic group making the…
Q: What else can acetyl coA be formed from?
A: Acetyl-coA: The oxidative decarboxylation of pyruvate from glycolysis which occurs in…
Q: What are the steps involved (in order) in the conversion of pyruvate to acetyl CoA?
A: Conversion of pyruvate to acetyl CoA: Pyruvate is the end product of glycolysis and acetyl CoA is…
Q: Why does it make metabolic sense for ADP and GDP to inhibit ribose phosphate pyrophosphokinase?
A: Ribose phosphate phosphokinase or ribose-phosphate pyrophosphokinase (RPPK) is a phosphoribosyl…
Q: In what condition and why is pyruvate converted to lactate?
A: Pyruvic acid is produced as a product of glycolysis, which is the anaerobic metabolism of glucose.…
Q: Although both acetyl-CoA and succinyl-CoA are high-energy thioesters, their chemical energy is used…
A: A tricarboxylic acid (TCA) cycle, commonly known as the Krebs or citric acid cycle, is the primary…
Q: What do you mean by acetyl-CoA carboxylase?
A: The term ‘Enzyme’ stands for the biochemical messengers present in the body. These secreted from…
Q: Why is pyruvate not oxidized to CO2 and H2O underanaerobic conditions?
A: Cellular respiration occurs in 3 stages namely pyruvate oxidation, the tricarboxylic acid cycle, and…
Q: What are the 3 modifications that prepare pyruvate for the Krebs Cycle?
A: Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids and is an organic acid and a…
Q: what is the metabolic reaction of propinoyl CoA carboxylase?
A: Propinoyl CoA carboxylase is an enzyme responsible for carboxylation reaction. Propinoyl CoA is…
Q: Give the process/pathway where each of the following enzymes is involved.
A: Fatty acid are carboxylic acid with hydrocarbon side chain. Fatty acid can be synthesized by de novo…
Q: Is the statement, "citrate carries acetyl CoA to the mitochondrial matrix which is the site of fatty…
A: Fatty acid biosynthesis is the sequential process that involves in synthesis of long-chain fatty…
Q: Why is oxaloacetate an intermediate in gluconeogenesis?
A: Glucose is the primary source of energy in the body. Glucose is broken down into pyruvate by…
Q: what is the inhibitor of Acetyl-Co
A: Fatty acid metabolism includes Fatty acid biosynthesis (an anabolic process) and β- oxidation of…
Q: what is the correct sequence of reactions on the given choices with regard to beta oxidation of…
A: Lipid is a biomolecule that is not soluble in water. It plays a vital role as an effective cell…
Q: What is the role of malonyl CoA in fatty acid synthesis?
A: Fatty acid synthesis takes place within the cytoplasm where the synthesis of fatty acid occurs from…
Q: Why is pyruvate referred to as the hub of glucose oxidation?
A: Glycolysis is the oxidation of glucose to produce carbon dioxide and water. Pyruvate is the…
Q: Why is acetyl-CoA considered the central molecule of metabolism?
A: Metabolism is the term used to describe set of chemical reactions that are involved in the living…
Q: What is the normal fate of citrate formed by the condensation of acetyl CoA with oxaloacetate?
A: Introduction: The oxaloacetate combines with acetyl CoA to form citrate which is the starting point…
Q: How would riboflavin deficiency affect the functioning of the tricarboxylic acid cycle?
A: “Since you have asked multiple questions, we will solve the first question for you. If youwant any…
Q: How Is Pyruvate Oxidatively Decarboxylatedto Acetyl-CoA
A: Oxidative decarboxylation is a process in which carbon dioxide is produced through removal of a…
Q: What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase…
A: Introduction Respiration is a metabolic process involving the oxidation of organic compounds to form…
Q: Why is NADH required for gluconeogenesis?
A: Glucose is the most simple form of carbohydrate. It is also the nutrient that is the most easiest to…
Q: Why is the TCA cycle is important for both anabolic and catabolic reactions?
A: After each turn of the TCA cycle, oxaloacetate is regenerated and can combine with another…
Q: Why is pyruvate converted to lactate under anaerobic conditions?
A: Anaerobic Glycolysis was the process of oxidation of glucose that takes place when the oxygen levels…
Q: What is the role of HMG CoA reductase in cholesterol and isoprenoid synthesis?
A: HMG-CoA reductase is the rate controlling enzyme of the mevalonate pathway, the metabolic pathway…
Q: If the carbonyl carbon of acetyl-CoA were marked with 14C, where would that carbon be located within…
A: Metabolism includes biosynthesis/ reduction (an anabolic process) and oxidation (catabolic…
Q: How does pyruvate from glycolysis get to the pyruvate dehydrogenase complex?
A: Pyruvate dehydrogenase complex : It is a complex of three enzymes that converts pyruvate into…
Q: What is the advantage of activating pyruvate kinase with fructose-1,6-bisphosphate?
A: Glycolysis is the metabolic pathway that converts glucose into pyruvate and hydrogen ion through…
Q: What are the health implications of a deficiency of the enzyme, pyruvate decarboxylase?
A: The pyruvate decarboxylase enzyme is involved in the conversion of pyruvate to acetaldehyde. This…
Q: Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate…
A: Guconeogenesis is the process whereby glucose is formed from non-carbohydrate metabolic substrate…
Q: Why is acetyl-CoA considered a “strategic intermediate” in respiration?
A: Respiration is the process of oxidation of nutrients to retrieve the energy stored in them.
Q: what are the components of Pyruvate dehydrogenase Enzyme complex ?
A: Pyruvate dehydrogenase Enzyme complex is made up of three Enzymes and requires 5 coenzymes .
Q: How many acetyl-CoA molecules can be produced from a 20-carbon chain free fatty acid?
A: A balanced diet is the prerequisite of all human beings to sustain life. A balanced diet contains…
Q: Explain why it makes metabolic sense for acetyl-CoA, which is not a substrate for gluconeogenesis,…
A: Acetyl-CoA : It is a molecule that participates in many biochemical reactions in protein,…
Q: Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate…
A: Guconeogenesis is the process whereby glucose is formed from non-carbohydrate metabolic substrate…
Q: what product comes from beta oxidation of oddnumbered fatty acids and is converted to succinyl coa
A: Beta-oxidation of fatty acid is the process of breaking down in the cytosol that leads to generating…
Q: Does thiamine pyrophosphate play a role in the reactions of the pentose phosphate pathway? If so,…
A: Yes, thiamine pyrophosphate plays a very important role in the reaction of the pentose phosphate…
Q: If acetyl-CoA containing radiolabeled carbons in the acetyl group was used to synthesize leucine,…
A: Amino acids are biosynthesized from the intermediates of glycolysis, tricarboxylic acid cycle or the…
Q: what is the metabolic reaction\pathway in which the propionyl CoA caboxylase evzyme is involved ? (…
A: The series of chemical events that keep organisms alive is known as metabolism. Food is converted to…
Q: What is the metabolic importance of malonyl-CoA?
A: Introduction: Malonyl-CoA is a malonic acid coenzyme A derivative. In the production of fatty acids…
Q: How is acetyl coA carboxylase being regulated?
A: Fatty acids are the components of lipids. Fatty acids act as energy source when there is no dietary…
Q: Does Pyruvate Dehydrogenase Complex have coenzymes and Allosteric regulation?
A: Pyruvate dehydrogenase complex (PDC) is a three-enzyme complex that decarboxylates pyruvate into…
Q: What are the five enzymes (including regulatory enzymes) that constitute the pyruvate dehydrogenase…
A: Introduction: The pyruvate dehydrogenase complex is a three-enzyme complex that transforms pyruvate…
Why is acetyl CoA an especially appropriate activator for pyruvate carboxylase?
Step by step
Solved in 2 steps
- Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.Why is pyruvate carboxylase constitutive and active in both glycolysis and gluconeogenesis?How many acetyl CoA molecules can be produced during the complete β-oxidation of this fatty acid?
- How many more acetyl CoA are generated from stearic acid than from linoleic acid during beta oxidation?How similar of an effect would a mutation in pyruvate dehydrogenase have, compared to a mutation in pyruvate carboxylase that blocks its ability to be regulated by acetyl-CoA?Explain why it makes metabolic sense for acetyl-CoA, which is not a substrate for gluconeogenesis, to activate pyruvate carboxylase.