When the net charge on either side of the plasma membrane is zero, what else is true? There is an equal number of K+ ions on each side of the plasma membrane. The K+ leak channels are open. The electrochemical potential across the membrane is zero. The resting membrane potential is between -20 mV and -200 mV.
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When the net charge on either side of the plasma membrane is zero, what else is true?
- There is an equal number of K+ ions on each side of the plasma membrane.
- The K+ leak channels are open.
- The
electrochemical potential across the membrane is zero. - The resting membrane potential is between -20 mV and -200 mV.
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- Assume that a membrane permeable to Na+ but not to Cl- separates two solutions. The concentration of sodium chloride on side 1 is higher than on side 2. Which of the following ionic movements would occur? a. Na+ would move until its concentration gradient is dissipated (until the concentration of Na+ on side 2 is the same as the concentration of Na+ on side 1). b. Cl- would move down its concentration gradient from side 1 to side 2. c. A membrane potential, negative on side 1, would develop. d. A membrane potential, positive on side 1, would develop. e. None of the preceding is correct.Describe the contribution of each of the following to establishing and maintaining membrane potential: (a) the Na+K+ pump, (b) passive movement of K+ across the membrane, (c) passive movement of Na+ across the membrane, and (d) the large intracellular anions.One of the important uses of the Nernst equation is in describing the flow of ions across plasma membranes. Ions move under the influence of two forces: the concentration gradient (given in electrical units by the Nernst equation) and the electrical gradient (given by the membrane voltage). This is summarized by Ohms law: Ix=Gx(VmEx) which describes the movement of ion x across the membrane. I is the current in amperes (A); G is the conductance, a measure of the permeability of x, in Siemens (S), which is I/V;Vm is the membrane voltage; and Ex is the equilibrium potential of ion x. Not only does this equation tell how large the current is, but it also tells what direction the current is flowing. By convention, a negative value of the current represents either a positive ion entering the cell or a negative ion leaving the cell. The opposite is true of a positive value of the current. a. Using the following information, calculate the magnitude of Na [ Na+ ]0=145mM,[ Na+ ]i=15mM,Gna+=1nS,Vm=70mV b. Is Na+ entering or leaving the cell? c. Is Na+ moving with or against the concentration gradient? Is it moving with or against the electrical gradient?
- The rate at which the Na+K+ pump operates is not constant but is controlled by a combined effect of changes in ICF Na+ concentration and ECF K+ concentration. Do you think the changes in both ICF Na+ and ECF K+ concentration following a series of action potentials in a neuron would accelerate, slow down, or have no effect on the Na+K+ pumps in this cell?The membrane potential for an excitable cell membrane is -70 mV, for sodium ions the Nernst equilibrium potential is +50 mV, the conductivity of the single sodium channel is 10 pS. What is the electrochemical potential difference that is the driving force for sodium ions to migrate? How much current flows through an open sodium channel under these conditions?What is the free energy change for the transport of calcium ions (Ca++) across a membrane from a region (left) where the concentration is 50 micromolar to a region (right) where the concentration is 50 micromolar? A membrane potential of 60 mV exists across the membrane where the right side is more negative than the left side. The temperature is 25 C.
- Which of the following statements regarding the equilibrium potential (Eion) of an ion is correct? The equilibrium potential for potassium is less negative than the resting membrane potential. The electrical force that acts upon potassium attracts potassium to the interstitium. The chemical force that acts upon sodium drives sodium out of the cell. At an ion’s equilibrium potential, the electrochemical force is zero.At the membrane of an axón, the action potential is -60 mV for K+ ions. Calculate the external and internal concentration ratios."The membrane potential arises from movements of charge that leave ion concentrations practically unaffected, causing only a very slight discrepancy in the number of positive and negative ions on the two sides of the membrane." is true or false.
- if an object b has a plasma sodium concentration of 135mOsm/L and an intracellular concentration of 4mOsm/L. It also has a plasma concentration of potassium of 20mOsm/L and an intracellular concentration of 200mOsm/L. studies identify that the cells have a permeability to potassium that is 10 times greater than sodium. What is the resting membrane potentialThe reason that resting membrane potential (RMP) is closer to the equilibrium potential of K+ (EK) rather than that of Na+ (ENa) is that… Group of answer choices -The driving force for Na+ ions at rest is high. -The membrane is much more permeable to Na+ ions than K+ ions at rest. -Only K+ ions have a concentration gradient, Na+ ions have approximately equal intracellular and extracellular concentrations -The membrane is much more permeable to K+ ions than Na+ ions at rest.What is an average range of millivolt difference between resting membrane potential and threshold potential? 150-300mV 1-2mV 0.005-500mV 15-30mV