Answered: Which of the following amino acid side…

Science

Chemistry

Which of the following amino acid side chains can form an imine with a substrate? CH2CNH2O 1 (CH2)4NH22 3 CH2OH4 CH2NH

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins

Section26.SE: Something Extra

Problem 61AP

See similar textbooks

Related questions

Q: A novel new method of peptide synthesis involves formation of an amide bond by reaction of an a-keto…

A: In this question, we want to draw curved arrows on the reactant Molecule. You can see details…

Q: Ninhydrin reacts with an amino acid to form a purple-colored compound. Propose a mechanism to…

A: Given,

Q: Draw the structures of the substrate (pNPP) and of the inhibitors (Pi and Phe). Consider them in the…

Q: What advantage does the enzyme gain by forming an imine?

A: Now when we consider a carbonyl compound which undergoes tautomerism to form enol under the…

Q: For each amino acid listed, tell whether its influence on tertiary structure is largely through…

A: Since we only answer up to 3 sub-parts, we’ll answer the first 3 sub-parts for you. Please resubmit…

Q: Hydrolysis C2H5MGCI В PCI3 A →2-Chlorobutane Н20 (ii)

A: In above given reaction A should be ethyne (A) which can be hydrolyzed into ethanal(B) . Ethanal…

Q: which enzyme mostly carried the following reaction NH2 indomethacin desisopropyl indomethacin

A: Human hepatic cyctochromes are the enzymes situated in the liver that are involve in the primary…

Q: Esterase hydrolyzes ester bonds. For simplicity, only the amino acids whose side-chains interact…

A: Introduction : Hydrolysis can be defined as a double decomposition reaction with water as one of…

Q: Which of the following amino acid side chains can help remove a proton from the a-carbon of an…

A: The carbon atom which is present just adjacent to the carbonyl group in aldehyde and ketone is…

Q: Suggest all the possible interactions that metoclopramide can interact with in physiological pH. CI…

A: To suggest all possible interactions that metoclopramide can have in physiological pH. The…

Q: reversibly in this glutamine analog is The group on carbon no. 6-Diazo-5-oxonorleucine (DON)…

A: 6-Diazo-5-oxonorleucine is a diazo compound which was synthesized using lysine and is used as a…

Q: Draw the mechanism for the reaction that removes an Fmoc group from an amino acid under these…

A: The mechanism for the reaction that removes an Fmoc group from an amino acid under the given…

Q: what is the mechanism of C20H23CIH9O to C19H21CIH9O conversion?

A: Interpretation- To write the mechanism of given C20H23ClHgO to C19H21ClHgO conversion -…

Q: Select below all the catalytic mechanisms used by chymotrypsin to convert substrate into product.

A: Chymotrypsin is a digestive enzyme belonging to a superfamily of enzymes called serine proteases. It…

Q: Q1. Eticlopride is a dopamine antagonist, which can block dopamine receptor sites and influence…

Q: CH. H CH;CH,CH,NH2 b. d. a. C. CH,CH, *NH2 strychnine (a powerful poison)

A: Given amines,

Q: . Delineate the detailed regulatory mechanism of activation of protein kinase A (PKA)…

A: Answer - According to the question - Protein kinase A (PKA) is activated by elevations in cAMP and…

Q: Sulfanilamide, a sulfur drug, acts as an antibiotic. Explain its mechanism of action in the context…

A: Ans. Sulfanilamide: An enzyme Inhibitor: Sulfa drugs work by binding and inhibiting a specific…

Q: Which of the following amines can be used to resolve a racemic mixture of amino acids?

A: Racemic mixture of amino acids: c). This compound has chiral carbon and can be used to resolve the…

Q: BCX4430 is active against the Ebola virus. What class of drugs would BCX4430 belong to and suggest a…

A: BCX4430 is an antiviral adenosine nucleoside analogue belonging to Galidesivir.

Q: 29. The pH maximum for the reaction of primary amine and an aldehyde to form an imine is: а. 2 b.…

A: 29) The pH maximum for the reaction of primary amine and an aldehyde to form an imine is 4.5.

Q: Carboxypeptidase A has esterase activity as well as peptidase activity, so it can hydrolyze ester…

Q: Predict the products formed in each of the following reactions, and write a balanced equation: (a)…

A: A chemical equation is called as the balanced equation when the total mole count of each element is…

Q: An enzyme catalyzes the hydrolysis of an ester with a certain activity, but this activity is lost in…

A: Any enzyme can be categorised a certain protein which loses its activity at a certain temperature,…

Q: Metalloproteases can contain a catalytic triad made up o O D(H₂O)D E(Ln*)S None of the choices are…

Q: What is the mechanism of action of the antibiotic drug Sulfanilamide in terms of enzyme inhibition?

Q: Draw the mechanism for the reaction that removes an Fmoc group from an amino acid under the…

A: The given reaction is,

Q: Protein synthesis in bacterial cells almost always starts with: a cysteine residue O could start…

Q: Which of the following amino acid side chains can form an imine with a substrate?

A: Imines are formed always when primary amines reacts with aldehyde or ketone.

Q: .N. HN- N. imidazolo[4,5,d]pyrimidine O imidazolo[5,4,b]pyimidine imidazolo[4,5,b]pyrimidine

A: Option A is correct.

Q: Some proteases are cysteine proteases and threonine proteases as opposed to serine proteases. What…

A: Given proteases, Cysteine proteases Threonine proteases Serine…

Q: Question attached

A: Standard entropy is the entropy content of one mole of pure substance under a standard state.The…

Q: The active site of an enzyme has a serine residue (shown below). Which of the following describes…

A: The structure of serine amino acid is as follows:

Q: OH HNL CN R' + HCN One of the proposed mechanisms for this enzyme is shown in the scheme below.…

Q: Metalloproteases can contain a catalytic triad made up of: D(H₂O)D E(Ln+)S None of the choices are…

A: Metalloproteases are enzymes whose catalytic mechanism for breaking peptide bonds involves a metal.…

Q: Identify the missing compounds D-F NaOCH3 MCPBA D. 1. CH3M9B E.

A: When 3-bromo-4-methylhexane is heated with NaOCH3 elimination reaction occurs to obtain an…

Q: Question attached

A: In chemical thermodynamics, entropy is the measure to calculate the randomness of the thermodynamic…

Q: Which of the following amino acid side chains can aid the departure of a leaving group?

A: The given amino acid side chains are,

Q: Vinylamycin, a depsipeptide with potent antimicrobial activities, can be synthesized via the…

A: In this reaction Fmoc is deprotected by using Piperidine to coupled with other acid in next step

Q: Draw the mechanism for the reaction that removes an Fmoc group froman amino acid under these…

A: The mechanism for the reaction that removes an Fmoc group from an amino acid under the given…

Q: Give a curved arrow mechanism for the hydrolysis of the dipeptide under an acidic condition. H20 H*…

A: In this question, we want to give a curved arrow mechanism. How we can give mechanism for this, you…

Q: Which type of noncovalent interaction would predominate between the R-groups of tryptophan and…

A: Non-covalent interaction may be defined as the interaction in which there is no sharing of electrons…

Q: Chorismate mutase is an enzyme that promotes a pericyclic reaction by forcing the substrate to…

A: Chorismate mutase is an enzyme that promotes a pericyclic reaction by forcing the substrate to…

Q: 1. Alkaline phosphatase has a key serine residue in the active site that is critical for biological…

A: The hydrolysis of phosphate ester proceeds via the key phosphoserine intermediate.

Q: In the design of H2 antagonist, the polar guanidine group was proposed to interact with the…

A: Introduction : Drug design is the inventive process of finding new medications based on the…

Q: On what amino acid do caspases specifically cleave their substrates? (Choose p20/p10 dimers cleave…

A: The correct matching is as follows:

Q: Dimethylphenyl-oxopropanoate decarboxylase catalyzes the following reaction. Draw the structure of…

A: Structure of the cofactor is :

Concept explainers

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.

Question

Which of the following amino acid side chains can form an imine with a substrate?

CH2CNH2
O

(CH2)4NH2
2 3

CH2OH
4

CH2
N
H

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

Step 2

Step 3

Step 4

Step 5

Trending now

This is a popular solution!

Step by step

Solved in 5 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Which of the following amino acid side chains can aid the departure of a leaving group?
Which of the following amino acid cannot bind a heme group using its side chain as an axial ligand? A. Lysine B. Valine C. Histidine D. Cystine
Reaction of a polypeptide with carboxypeptidase A releases Met. The polypeptide undergoes partial hydrolysis to give the following peptides. What is the sequence of the polypeptide? 1. Ser, Lys, Trp 4. Leu, Glu, Ser 7. Glu, His 10. Glu, His, Val 2. Gly, His, Ala 5. Met, Ala, Gly 8. Leu, Lys, Trp 11. Trp, Leu, Glu 3. Glu, Val, Ser 6. Ser, Lys, Val 9. Lys, Ser 12. Ala, Met
Which of the following substituent is a meta-directing deactivator? a amino group b halogenation group c phenyl group d carboxyl group
Draw the amino acids and peptide fragments formed when the decapeptide A–P–F–L–K–W–S–G–R–G is treated with each reagent or enzyme: (a) chymotrypsin; 8 pt helvetica roman (b) trypsin; (c) carboxypeptidase; (d) C6H5N = C = S.
Draw the structures of the substrate (pNPP) and of the inhibitors (Pi and Phe). Consider them in the fully deprotonated states. What similarities can you detect between each inhibitor and the substrate?
What type of reaction would a PLP-containing enzyme catalyze if the bond most perpendicular to PLP was a C-COO- bond? A、racemization B、transamination C、aldol cleavage D、decarboxylation
lysozyme catalyzes the hydrolysis of a carbohydrate linkage in part of the bacterial wall. The active site of the lysozyme contains aspartate and glutamate side chains. 1. lysozyme catalyzes this reaction with a catalytic Zn 2+ ion. propose a mechanism.
Predict the products formed in each of the following reactions, and write a balanced equation: (a) CH3NHNH21g2 + O21g2 ¡ ? (b) Mg3P21s2 + H2O1I2?
Which one will make the largest contribution to hydrophobic interactions via LDFs within the active site of an enzyme?
Chorismate mutase is an enzyme that promotes a pericyclic reaction by forcing the substrate to assume the conformation needed for the reaction. The product of the pericyclic reaction is prephenate that is subsequently converted into the amino acids phenylalanine and tyrosine. What kind of a pericyclic reaction does chorismate mutase catalyze?
Show the mechanism and explain how the Ala-Val-Ile peptide bond is formed.