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Which of the following statements about how cells control the size of the poly-A tail on mRNA molecules in order to regulate translation initiation is FALSE? To inhibit translation initiation, a protein called CPEB binds to the CPE sequence on the mRNA. This will then bring in an enzyme called PARN. O If a kinase inhibitor was introduced, then Maskin and PARN would be able to continue to exert their inhibitory effect on translation initiation. To initiate translation, the protein CPEB gets phosphorylated by a specific kinase. This causes a conformational change that excludes both Maskin and PARN. O If a kinase inhibitor was introduced, then CPEB would be phosphorylated, so no conformational change would occur. Without Maskin and PARN, the poly-A tail can extend and eIF4E and eIF4G can interact with each other to initiate translation.

Which of the following statements about how cells control the size of the poly-A tail on mRNA molecules in order to regulate translation initiation is FALSE? To inhibit translation initiation, a protein called CPEB binds to the CPE sequence on the mRNA. This will then bring in an enzyme called PARN. O If a kinase inhibitor was introduced, then Maskin and PARN would be able to continue to exert their inhibitory effect on translation initiation. To initiate translation, the protein CPEB gets phosphorylated by a specific kinase. This causes a conformational change that excludes both Maskin and PARN. O If a kinase inhibitor was introduced, then CPEB would be phosphorylated, so no conformational change would occur. Without Maskin and PARN, the poly-A tail can extend and eIF4E and eIF4G can interact with each other to initiate translation.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 8 Which of the following statements about how cells control the size of the poly-A tail on mRNA molecules in order to regulate translation initiation is FALSE? To inhibit translation initiation, a protein called CPEB binds to the CPE sequence on the mRNA. This will then bring in an enzyme called PARN. O If a kinase inhibitor was introduced, then Maskin and PARN would be able to continue to exert their inhibitory effect on translation initiation. To initiate translation, the protein CPEB gets phosphorylated by a specific kinase. This causes a conformational change that excludes both Maskin and PARN. If a kinase inhibitor was introduced, then CPEB would be phosphorylated, so no conformational change would occur. Without Maskin and PARN, the poly-A tail can extend and elF4E and eIF4G can interact with each other to initiate translation. O O O O O
Transcribed Image Text:QUESTION 8 Which of the following statements about how cells control the size of the poly-A tail on mRNA molecules in order to regulate translation initiation is FALSE? To inhibit translation initiation, a protein called CPEB binds to the CPE sequence on the mRNA. This will then bring in an enzyme called PARN. O If a kinase inhibitor was introduced, then Maskin and PARN would be able to continue to exert their inhibitory effect on translation initiation. To initiate translation, the protein CPEB gets phosphorylated by a specific kinase. This causes a conformational change that excludes both Maskin and PARN. If a kinase inhibitor was introduced, then CPEB would be phosphorylated, so no conformational change would occur. Without Maskin and PARN, the poly-A tail can extend and elF4E and eIF4G can interact with each other to initiate translation. O O O O O
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