13 Ais a normal cellular gene that through aan oncogene.OA) proto-oncogene...loss-of-functionB) proto-oncogene...gain-of-functionC) tumor suppressor gene...loss-of-functionD) tumor suppressor gene...gain-of-functionmutation becomes

Name: 13 Ais a normal cellular gene that through aan oncogene.OA) proto-onco
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Description: 13 Ais a normal cellular gene that through aan oncogene.OA) proto-oncogene...loss-of-functionB) proto-oncogene...gain-of-functionC) tumor suppressor gene...loss-of-functionD) tumor suppressor gene...gain-of-functionmutation becomes

An oncogene is a cancer-causing gene that has been mutated. A proto-oncogene is a type of oncogene…

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Biology

is a normal cellular gene that through a A an oncogene. OA) proto-oncogene...loss-of-function OB) proto-oncogene...gain-of-function C) tumor suppressor gene...loss-of-function D) tumor suppressor gene...gain-of-function mutation becomes

is a normal cellular gene that through a A an oncogene. OA) proto-oncogene...loss-of-function OB) proto-oncogene...gain-of-function C) tumor suppressor gene...loss-of-function D) tumor suppressor gene...gain-of-function mutation becomes

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter6: Reproduction At The Cellular Level

Section: Chapter Questions

Problem 8RQ: ________ are changes to the nucleotides in a segment of DNA that codes for a protein. a....

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What is the difference between a proto-oncogene and a tumor-suppressor gene?
________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulators
Most forms of cancer involvea. the activation of a single oncogene.b. the inactivation of a single tumor-suppressor gene.c. the activation of multiple oncogenes.d. the activation of multiple oncogenes and the inactivation ofmultiple tumor-suppressor genes.
Tumor Suppressor Genes are often called as gatekeepers because: a. They signify their involvement in governing the dynamics of cell proliferation b. They allow tumors to proliferate at an uncontrolled rate c. To allow a transport channel of suppressors d. They are not referred to as ?gatekeepers?
An oncogene is produced from a that has acquired a .a. proto-oncogene, loss-of-function mutationb. proto-oncogene, gain-of-function mutationc. tumor-suppressor gene, loss-of-function mutationd. tumor-suppressor gene, gain-of-function mutation
Which of the following statements correctly describes a characteristic of tumor-suppressor gene? a) they are frequently overexpressed in cancerous cells. b) they are cancer-causing genes introduced into cells by viruses. c) they encode proteins that help prevent uncontrolled cell growth. d) they often encode proteins that stimulate the cell cycle.
Define oncogene, proto-oncogene, and tumor-suppressor gene.
Which of the following is true of tumor suppressor genes? Group of answer choices a) If this gene is overactive, it becomes an oncogene b) If one of the alleles is mutated, there is usually little effect. Two inactivating mutations are usually required for loss of function (recessive mutation). c) If one copy is lost, the gene no longer functions (dominant mutation) d) Tumor suppressors genes usually cause mitosis or cell growth e) Tumor suppressor genes decrease apoptosis
Define the following terms: tumor, neoplasia, anaplasia, metastasis, proto-oncogene, oncogene, and tumor suppressor gene.
Why does a single mutation in a proto-oncogene, turning it into an oncogene potentially lead to a cancerous phenotype, while it takes two mutations in tumor suppressor genes to lead to a cancerous phenotype?
Describe the genetic changes that convert proto-oncogenesinto oncogenes or inactivate tumor-suppressor genes.
Why are oncogenes usually dominant in their action, whereas tumor-suppressor genes are recessive?